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Histiocytic necrotizing lymphadenitis (kikuchi's disease): Cytologic diagnosis by fine‐needle biopsy

1993; Wiley; Volume: 9; Issue: 4 Linguagem: Inglês

10.1002/dc.2840090414

8755-1039

Merle L. Greenberg, Lyn Cartwright, David McDonald,

Bartonella species infections research

Abstract A cytologic diagnosis of histiocytic nerotizing lymphadenitis (Kikuchi's lymphadenitis) was made in a 14‐yr‐old female with cervical lymphadenopathy, Fever, neutropenia, and hepatosplenomegaly. A predominance of reticulum cells, foamy macrophages, and karyorrhectic debirs are cluse to the diagnosis in the fine‐needle biopsy smears. Subsequent histology confirmed the diagnosis of Kikuchi's lymphadenitis. The differential diagnoses are discussed including malignant lymphoma, which was excluded by morphology as well as flow cytometry and polymerase chain reaction (PCR) studies.