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BIBTEX RIS

The Nutrient-Responsive Transcription Factor TFE3 Promotes Autophagy, Lysosomal Biogenesis, and Clearance of Cellular Debris

2014; American Association for the Advancement of Science; Volume: 7; Issue: 309 Linguagem: Inglês

10.1126/scisignal.2004754

ISSN

1937-9145

Autores

José A. Martina, Heba I. Diab, Lishu Li, Jeong‐A Lim, Simona Patange, Nina Raben, Rosa Puertollano,

Tópico(s)

Calcium signaling and nucleotide metabolism

Resumo

Enhancing TFE3 activity to promote expression of lysosome-associated genes may be beneficial in treating lysosomal storage disorders.

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