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Avaliação da porosidade de microcápsulas contendo proteína bioativa por porosimetria de mercúrio e adsorção de nitrogênio

2011; Brazilian Chemical Society; Volume: 34; Issue: 9 Linguagem: Inglês

10.1590/s0100-40422011000900018

1678-7064

Luciana Helena Maia Porte, Maria Helena Miguez Rocha Leão, Alexandre Porte,

Electrospun Nanofibers in Biomedical Applications

MICROCAPSULES CONTAINING BIOCATIVE PROTEIN BY MERCURY POROSIMETRY AND NITROGEN ADSORPTION.Microcapsules containing lactoferrin were produced by spray drying using dextrin:octenylsuccinate starch, as wall materials.Porosity characteristics of spray-dried microcapsules were investigated by mercury intrusion porosimetry and nitrogen adsorption.The outer and inner structures of microcapsules were studied by Scanning Electron Microscopy and sizes were determined by Laser Diffraction.Results indicate that all microcapsules presents adsorption isotherm of type II and that micropores on the microcapsules surface will be very few or none.Our results show that microstructure, surface area and size of microcapsules are affected by dextrin: octenylsuccinate starch proportion.Pore characteristics for various microcapsules are found to be different.