Core–Shell Pd@Au Nanoplates as Theranostic Agents for In‐Vivo Photoacoustic Imaging, CT Imaging, and Photothermal Therapy
2014; Volume: 26; Issue: 48 Linguagem: Inglês
10.1002/adma.201404013
ISSN1521-4095
AutoresMei Chen, Shaoheng Tang, Zhide Guo, Xiaoyong Wang, Shiguang Mo, Xiaoqing Huang, Gang Liu, Nanfeng Zheng,
Tópico(s)Extracellular vesicles in disease
ResumoUniform plasmonic Pd@Au core–shell bimetallic nanoplates are synthesized by seeded growth strategy. Surface modified with SH-PEG makes it good biocompatibility, prolonged blood circulation, and relatively high tumor accumulation. Enhanced tumor contrast effects can be obtained for in vivo photoacoustic/CT imaging after intravenous injection of Pd@Au-PEG. Moreover, efficient photothermal tumor ablation is achieved, guided by the imaging techniques. This work promises further exploration of the superiority of 2D nanostructures for in vivo biomedical applications.
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