Rapid Diagnostec Test for Ocular Adenovirus
1988; Elsevier BV; Volume: 95; Issue: 4 Linguagem: Inglês
10.1016/s0161-6420(88)33168-4
ISSN1549-4713
AutoresLee A. Wiley, David Springer, Regis P. Kowalski, Robert C. Arffa, Melvin I. Roat, R A Thoft, Y. Jerold Gordon,
Tópico(s)Cytomegalovirus and herpesvirus research
ResumoAbstract A new, direct, enzyme immunoassay test (Adenoclone, Cambridge BioScience, Hopkinton, MA) was evaluated for the rapid diagnosis of ocular adenovirus infections. In 36 culture-proven cases of adenovirus ocular infection, direct Adenoclone testing of conjunctival swabs was positive in 24 of 31 patients (77%) tested within 1 week of onset of symptoms, and in one of five patients (20%) who presented after 1 week ( P < 0.02). Overall sensitivity was 69%, whereas specificity was 100%. The authors conclude that a positive Adenoclone test is reliable in the rapid diagnosis of early adenovirus ocular infections.
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