A Case of decapitated spermatozoa in an infertile man
2009; Wiley; Volume: 27; Issue: 3 Linguagem: Inglês
10.1111/j.1439-0272.1995.tb01089.x
ISSN1439-0272
AutoresYoshiro Toyama, T. Kazama, Hideki Fuse, Takashi Katayama,
Tópico(s)Reproductive Health and Technologies
ResumoAndrologiaVolume 27, Issue 3 p. 165-170 A Case of decapitated spermatozoa in an infertile man Y. Toyama, Corresponding Author Y. Toyama Department of Anatomy, School of Medicine, Chiba University, Chiba, JapanDepartment of Anatomy, School of Medicine, Chiba University, Chuou, Chiba 260, Japan.Search for more papers by this authorT. Kazama, T. Kazama Department of Urology, Toyama Medical and Pharmaceutical University, Toyama, JapanSearch for more papers by this authorH. Fuse, H. Fuse Department of Urology, Toyama Medical and Pharmaceutical University, Toyama, JapanSearch for more papers by this authorT. Katayama, T. Katayama Department of Urology, Toyama Medical and Pharmaceutical University, Toyama, JapanSearch for more papers by this author Y. Toyama, Corresponding Author Y. Toyama Department of Anatomy, School of Medicine, Chiba University, Chiba, JapanDepartment of Anatomy, School of Medicine, Chiba University, Chuou, Chiba 260, Japan.Search for more papers by this authorT. Kazama, T. Kazama Department of Urology, Toyama Medical and Pharmaceutical University, Toyama, JapanSearch for more papers by this authorH. Fuse, H. Fuse Department of Urology, Toyama Medical and Pharmaceutical University, Toyama, JapanSearch for more papers by this authorT. Katayama, T. Katayama Department of Urology, Toyama Medical and Pharmaceutical University, Toyama, JapanSearch for more papers by this author First published: May‐June 1995 https://doi.org/10.1111/j.1439-0272.1995.tb01089.xCitations: 21AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract Summary A case of headless or decapitated spermatozoa of an infertile man is reported. The 33-year-old patient showed almost normal spermi-ogram except for a high percentage (more than 90%) of headless spermatozoa. Both hypoosmotic swelling and zona-free hamster egg tests showed that most headless spermatozoa appeared to be normal in their function as tails. The ultrastructure of the ejaculated spermatozoa was observed using a surface replica method and by conventional ultrathin sectioning. The headless spermatozoa were almost normal in structure except for the absence of the head. Tailless heads were rarely observed. Varieties of ultrastructural abnormalities were observed in spermatozoa heads. Among them, abnormalities in the nuclear membrane covering the posterior pole of the nucleus were prominent. The implantation fossa and the basal plate were not formed. Instead, the nuclear membrane with numerous nuclear pores was found in this region. The decapitation seemed to take place between the region of the basal plate and the proximal centriole. References Alun-Jones W (1962) Abnormal morphology of the spermatozoa in Guernsey bulls. Br Vet J 118: 257–261. Google Scholar Barth AD, Oko RJ (1989) Abnormal morphology of bovine spermatozoa. Iowa State University Press, Ames, Iowa. Google Scholar Baccetti B, Selmi MG, Soldani P (1984) Morphogenesis of 'decapitated' spermatozoa in a man. J Reprod Fertil 70: 395–397. 10.1530/jrf.0.0700395 CASPubMedWeb of Science®Google Scholar Baccetti B, Burrini AG, Collodel G, Magnano AR, Piomboni P, Renieri T, Sensini C (1989) Morphogenesis of the decapitated and decaudated sperm defect in two brothers. Gamete Res 23: 181–188. 10.1002/mrd.1120230205 CASPubMedWeb of Science®Google Scholar Blom E, Birch-Andersen A (1970) Ultrastructure of the 'decapitated sperm defect' in Guernsey bulls. J Reprod Fertil 23: 67–72. 10.1530/jrf.0.0230067 CASPubMedWeb of Science®Google Scholar Chemes HE, Carizza C, Scarinci F, Brugo S, Neuspiller N, Schwarsztein L (1987) Lack of a head in human spermatozoa from sterile patients: a syndrome associated with impaired fertilization. Fertil Steril 47: 310–316. 10.1016/S0015-0282(16)50011-9 CASPubMedWeb of Science®Google Scholar David G, Bisson JP, Czyglik F, Jouannet P, Gernigon C (1975) Anomalies morphologiques du spermatozoide humain. 1) Propositions pour un système de classification. J Gyn Obst Biol Reprod 4:Suppl 1: 17–36. Google Scholar Friend DS, Fawcett DW (1974) Membrane differentiations in freeze-fractured mammalian sperm. J Cell Biol 63: 641–664. 10.1083/jcb.63.2.641 CASPubMedWeb of Science®Google Scholar Fujita T, Miyoshi M, Tokunaga J (1970) Scanning and transmission electron microscopy of human ejaculate spermatozoa with special reference to their abnormal forms. Z Zellforsch 105: 483–497. 10.1007/BF00335423 CASPubMedWeb of Science®Google Scholar Holstein AF (1975) Morphologische Studien an abnormen Spermatiden und Spermatozoen des Menschen. Virchows Arch A Path Anat Histol 367: 93–112. 10.1007/BF00430948 CASPubMedWeb of Science®Google Scholar Holstein AF, Schill WB, Breucker H (1986) Dissociated centriole development as a case of spermatid malformation in man. J Reprod Fertil 78: 719–725. 10.1530/jrf.0.0780719 CASPubMedWeb of Science®Google Scholar Holstein AF, Roosen-Runge EC, Schirren C (1988) Illustrated pathology of human spermatogenesis. Grosse, Berlin. Google Scholar Hunter DG, Kretzer FL (1986) Abnormal axonemes in sperm of fertile men. Arch Androl 16: 1–12. 10.3109/01485018608986917 CASPubMedWeb of Science®Google Scholar Lüders G (1976) Ein Defekt der Kopf-Schwanz Verknüpfung bei menschlichen Spermatozoen. Andrologia 8: 365–368. 10.1111/j.1439-0272.1976.tb01672.x CASPubMedWeb of Science®Google Scholar Perotti ME, Giarola A, Gioria M (1981) Ultrastructural study of the decapitated sperm defect in an infertile man. J Reprod Fertil 63: 543–549. 10.1530/jrf.0.0630543 CASPubMedWeb of Science®Google Scholar Stackpole CW, Devorkin D (1974) Membrane organization in mouse spermatozoa revealed by freeze-etching. J Ultrastruct Res 49: 167–187. 10.1016/S0022-5320(74)80030-4 CASPubMedWeb of Science®Google Scholar Toyama Y (1989) In utero changes of the plasma membrane in the head region of the rat spermatozoa. J Electron Microsc 38: 148–154. CASPubMedWeb of Science®Google Scholar Toyama Y, Nagano T (1988) Maturation changes of the plasma membrane of rat spermatozoa observed by surface replica, rapid-freeze and deep-etch, and freeze-fracture methods. Anat Rec 220: 43–50. 10.1002/ar.1092200106 CASPubMedWeb of Science®Google Scholar Toyama Y, Itoh Y (1993) Ultrastructural features and pathogenesis of knobbed spermatozoa in a boar. Am J Vet Res 54: 743–749. CASPubMedWeb of Science®Google Scholar Wright PJ (1974) Detached heads in the ejaculate of a Hereford bull. Aust Vet J 50: 39–40. 10.1111/j.1751-0813.1974.tb09375.x CASPubMedWeb of Science®Google Scholar Zamboni L (1987) The ultrastructural pathology of the spermatozoon as a cause of infertility: the role of electron microscopy in the evaluation of semen quality. Fertil Steril 48: 711–734. 10.1016/S0015-0282(16)59520-X PubMedWeb of Science®Google Scholar Citing Literature Volume27, Issue3May‐June 1995Pages 165-170 ReferencesRelatedInformation
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