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BIBTEX RIS

Safe choice of metals in food bioprocess enzyme-mimicry?

2002; Elsevier BV; Volume: 21; Issue: 1 Linguagem: Inglês

10.1016/s0167-7799(02)00005-7

ISSN

0167-9430

Autores

Alan Wiseman, Len Woods,

Tópico(s)

Extraction and Separation Processes

Resumo

The association of metals with proteins confers greatly enhanced biocatalytic activity. For example, powdered iron can trigger a rapid decomposition of hydrogen peroxide into water and oxygen. However, such a reaction is a form of enzyme mimic and catalase does it ∼105 faster. The search for full understanding of the enhanced role of the protein moiety is a laudable application of in silico molecular modelling to complement ‘real lab’ studies of enzyme specificity and efficacy [ 1 Wiseman A. Woods L.F.J. Can real lab supersede virtual-ligand promises?. Trends Pharm. Sci. 2002; 23: 261 Abstract Full Text Full Text PDF PubMed Scopus (10) Google Scholar ].

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