Portal de Periódicos da CAPES

Pentobarbitone inhibits the stress response to transport in male goats

1991; Elsevier BV; Volume: 147; Issue: 1 Linguagem: Inglês

10.1016/0007-1935(91)90065-u

1879-3606

A.A. Sanhouri, R. S. Jones, H. Dobson,

Reproductive Physiology in Livestock

Pentobarbitone (20 mg/kg i.v.) blocked plasma cortisol release when administered either before a 20 min journey or during a 2 h journey. This confirms that pentobarbitone can block stimulated, as well as resting, cortisol secretion. In general, blood glucose concentrations were not increased above 90 mg/100 ml until at least 30 min after the start of transport; however, this increase was also blocked by pentobarbitone administered 30 min into the 2 h journey. Significant increases in respiratory and heart rates occurred within 15 min of the start of transport; pentobarbitone caused an immediate decrease in these parameters. In conclusion, pentobarbitone was shown to reverse many metabolic changes induced by transport.