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Coronary Calcium, Race, and Genes

2002; Lippincott Williams & Wilkins; Volume: 22; Issue: 3 Linguagem: Inglês

10.1161/hq0302.105366

1524-4636

Teri A. Manolio, Diane E. Bild,

Advanced MRI Techniques and Applications

easurement of coronary calcium has become a useful tool in the investigation of coronary disease and coronary risk, as evidenced by the companion articles in this issue examining the relationship of race and genetic factors to coronary calcium. 1,2Newman et al 1 report racial differences in coronary calcium measures in older adults participating in the Cardiovascular Health Study.Among 471 white and 143 black participants with an average age of 80 years, median coronary calcium scores were lower in blacks than in whites, particularly in men, even after adjustment for other black-white differences.Black men were only 20% as likely, and black women 71% as likely, as whites to have increased calcium scores.In the small subgroup of participants with myocardial infarction, who might be expected to be more similar, calcium scores still were lower among blacks than whites.