Hodgkin disease in a patient with common variable immunodeficiency
1989; Wiley; Volume: 32; Issue: 2 Linguagem: Inglês
10.1002/ajh.2830320212
ISSN1096-8652
AutoresSusan M. Fesus, Fredrick B. Hagemeister, John T. Manning,
Tópico(s)Cystic Fibrosis Research Advances
ResumoAbstract Extensive extralymphatic Hodgkin disease developed in a young man with common variable immunodeficiency manifested by hypogammaglobulinemia, recurrent sinopulmonary infections, and multiple autoimmune phenomena. Both humoral and cell‐mediated immune dysfunction were present prior to treatment. After two cycles of chemotherapy, irreversible shock developed, and death occurred secondary to overwhelming infection in spite of prophylactic gammaglobuiin replacement. The unusual features of this patient's case of extralymphatic Hodgkin disease in association with a primary immunodeficiency disorder have not been previously reported.
Referência(s)