Ultrastructural evidence of dopaminergic input to enkephalinergic neurons in rat neostriatum
1986; Elsevier BV; Volume: 367; Issue: 1-2 Linguagem: Inglês
10.1016/0006-8993(86)91622-7
ISSN1872-6240
AutoresYoshiyuki Kubota, Shinobu Inagaki, S. Kito, Hiroshi Takagi, A. David Smith,
Tópico(s)Neuroscience and Neuropharmacology Research
ResumoThe synaptic relationship between neuronal structures reacting with antibodies to tyrosine hydroxylase (TH) and Leu- or Met-enkephalin (ENK) was studied by the 'mirror technique' in adjacent sections of rat neostriatum. TH-immunoreactive (TH-IR) axonal boutons surrounding the neural perikarya and proximal dendrites of ENK-immunoreactive (ENK-IR) neurons were very thin (0.1–0.4 μm). They contained many small clear vesicles and sometimes had symmetrical membrane specializations. This provides morphological evidence for catecholaminergic, presumably dopaminergic inputs to rat striatal enkephalin neurons.
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