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Experimental infections of the musculoskeletal system: evaluation with MR imaging and Tc-99m MDP and Ga-67 scintigraphy.

1988; Radiological Society of North America; Volume: 167; Issue: 1 Linguagem: Inglês

10.1148/radiology.167.1.3162326

1527-1315

J Beltran, Robert B. McGhee, Phillip Shaffer, John O. Olsen, William F. Bennett, Trenton R. Foster, M S McCalla, Lilliana Iskra, R.L. Blagg, D S Biller,

Medical Imaging and Pathology Studies

Acute osteomyelitis, soft-tissue infection, or both were experimentally produced in 38 New Zealand white rabbits, and three-phase technetium-99m methylene diphosphonate, gallium-67, and magnetic resonance (MR) images were obtained 7 or 14 days after infection. There was no significant difference between radionuclide studies and MR images in the detection of osteomyelitis, but MR imaging was significantly more sensitive (100% vs. 69%; P less than .01) in the detection of soft-tissue infection. In addition, cellulitis could not be distinguished from soft-tissue abscess on radionuclide studies, whereas MR imaging was 92% accurate in depicting soft-tissue abscesses. Further research is necessary to determine how to relate these findings to true human clinical situations.