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Artigo Revisado por pares
BIBTEX RIS

Acute Iron Intoxication

1965; Massachusetts Medical Society; Volume: 273; Issue: 21 Linguagem: Inglês

10.1056/nejm196511182732103

ISSN

1533-4406

Autores

Julian Jagobs, Harry L. Greene, Benjamin R. Gendel,

Tópico(s)

Pharmacological Effects and Toxicity Studies

Resumo

ACCIDENTAL poisoning by iron compounds continues to be a common pediatric problem.1 2 3 This brief review includes the current thoughts on the pathophysiology of iron poisoning, the results of treatment with a new chelating agent, deferoxamine, in 6 previously published cases and 5 new cases treated by us, including a detailed case report. Information is given regarding availability of the drug for clinical use in the treatment of acute iron poisoning.Clinical FeaturesThe clinical features of iron intoxication are summarized in Table 1. The patient ingesting an overdose of iron may proceed through four stages.4 Stage 1 occurs from immediately to . . .

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