Fluorescent Polystyrene–Fe 3 O 4 Composite Nanospheres for In Vivo Imaging and Hyperthermia
2009; Volume: 21; Issue: 21 Linguagem: Inglês
10.1002/adma.200803159
ISSN1521-4095
AutoresDonglu Shi, Hoonsung Cho, Yan Chen, Hong Xu, Hongchen Gu, Jie Lian, Wei Wang, Guokui Liu, Christopher Huth, Lumin Wang, Rodney C. Ewing, Sergei Budko, Giovanni M. Pauletti, Zhongyun Dong,
Tópico(s)Advanced biosensing and bioanalysis techniques
ResumoQuantum dots (QDs) are immobilized on the surfaces of magnetic Fe3O4-composite nanospheres (MNSs, see figure). The QDs exhibit intense visible-light emission in fluorescence spectroscopy and successfully facilitate, for the first time, in vivo soft-tissue imaging in live mice. The Fe3O4 nanoparticles respond to an external magnetic field by increasing the temperature of the surrounding environment (i.e., hyperthermia), which can be used therapeutically.
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