Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods
2004; Lippincott Williams & Wilkins; Volume: 24; Issue: 1 Linguagem: Inglês
10.1097/00041327-200403000-00021
ISSN1536-5166
Autores Tópico(s)Glaucoma and retinal disorders
ResumoSystematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods, Richard S. Smith, Simon W.M. John, Patsy M. Nishina, and John P. Sundberg. CRC Press, Boca Raton, FL, 2002. ISBN 0-849-30864-X. Price: $139.95 Scope: Scientists drawn predominantly from The Jackson Laboratory in Bar Harbor, Maine have written this compendium of the literature with original material on the normal anatomy, development, general pathology, and methodology for evaluation of the mouse eye and adnexa. Contents: Organization is logically accomplished with four sections. Section I tells about Regional Anatomy and Development, a review of normal gross and microscopic features of the mouse eye. Section II discusses Issues in Mutant Mouse Evaluation, wherein mouse eye disease is reviewed, with an emphasis on genetics. Mutagenesis issues peculiar to the mouse are discussed. Section III, of Regional Ocular Pathology, offers a review of histopathology of the mouse eye. Section IV, a synopsis of Biomethods, discusses the methodology of mouse necropsy, histologic examination, and techniques of mouse eye examination in vivo. Strengths: This is a useful reference, well-organized for the researcher reviewing mouse anatomy and examination techniques. For the ophthalmologist, it is interesting reading, my favorite chapter is Heckenlively’s section on the mouse ERG. The similarities between human and mouse eye anatomy and pathology are interesting, highlighted by the cover itself showing histology of the mouse anterior chamber angle. The book comes with a CD-ROM containing color photographs that supplement the black and white pictures within the text. It is all extensively referenced. Weaknesses: I do not recommend this book for initial learners in the field, but rather as a reference and source of literature review. Critical Appraisal: Dr. Smith, the principal author, brings ideal credentials and skills as an ophthalmologist, ophthalmic pathologist, and research scientist to a stellar array of contributors who acquit themselves well in this awesome task of teaching about the mouse eye. They have created what should be an indispensable reference in the field of genetics and development, which has become especially exciting with recent strides in the sequencing and understanding of the mouse and human genomes. Mitchell Vincent Gossman, MD St. Cloud, Minnesota
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