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BIBTEX RIS

Evaluation of bone metastases from breast cancer by bone scintigraphy and positron emission tomography/computed tomography imaging

2014; Elsevier BV; Volume: 180; Linguagem: Inglês

10.1016/j.ejogrb.2014.06.021

1872-7654

Ary Oliveira Pires, Umbelina Soares Borges, Pedro Vitor Lopes‐Costa, Luíz Henrique Gebrim, Benedito B. da Silva,

Cancer Diagnosis and Treatment

Objective The aim of this study was to compare bone scintigraphy (BS) and positron emission tomography/computed tomography (PET/CT) for the detection of bone metastases from breast cancer. Study design Twenty patients with breast cancer and bone pain were submitted to both bone scintigraphy and 18-F-fluorodeoxyglucose PET/CT imaging between July 2012 and June 2013. Scintigraphy was performed following an intravenous injection of technetium-99m-methylene diphosphonate (99mTc-MDP) around 10 days before the PET/CT scan, performed using an intravenous injection of 18-F-fluorodeoxyglucose followed by whole-body computed tomography (CT) to characterize metastases by both methods. Student's t-test for paired samples was used in the comparative data analysis, with significance at p < 0.05. Results CT identified 429 metastatic implants in the 20 patients, with scintigraphy showing 244 of these lesions (57%) and PET/CT showing 307 (72%); however, there was no statistically significant difference between the mean number of lesions detected per patient with the two imaging modalities (p = 0.367). Conclusion In the present study, no difference was found between PET/CT and bone scintigraphy in the detection of bone metastases from breast cancer.