Magnetic resonance imaging diagnosis of disseminated necrotizing leukoencephalopathy

1987; Elsevier BV; Volume: 11; Issue: 1 Linguagem: Inglês

10.1016/0149-936x(87)90031-2

ISSN

1878-1993

Autores

Scott W. Atlas, Robert I. Grossman, Roger J. Packer, Herbert I. Goldberg, David B. Hackney, Robert A. Zimmerman, Larissa T. Bilaniuk,

Tópico(s)

Infectious Encephalopathies and Encephalitis

Resumo

Disseminated necrotizing leukoencephalopathy is a rare syndrome of progressive neurologic deterioration seen most often in patients who have received central nervous system irradiation combined with intrathecal or systemic chemotherapy in the treatment or prophylaxis of various malignancies. Magnetic resonance imaging was more sensitive than computed tomography in detecting white matter abnormalities in the case of disseminated necrotizing leukoencephalopathy reported here. Magnetic resonance imaging may be useful in diagnosing incipient white matter changes in disseminated necrotizing leukoencephalopathy, thus permitting early, appropriate therapeutic modifications.

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