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Variegated Dermoscopy of in situ Melanoma

2012; Karger Publishers; Volume: 224; Issue: 3 Linguagem: Inglês

10.1159/000338696

1421-9832

Stefania Seidenari, Sara Bassoli, Stefania Borsari, C. Ferrari, Francesca Giusti, Giovanni Ponti, Carlo Tomasini, Cristina Magnoni,

Nonmelanoma Skin Cancer Studies

<b><i>Background:</i></b> Melanomas in situ (MIS) are difficult to diagnose, lacking well-established dermoscopic descriptors. <b><i>Objective:</i></b> The aim of this study was to<b> </b>improve the identification of early melanomas describing the variegated dermoscopic features of MIS and their correlation with demographic and clinical aspects. <b><i>Methods:</i></b> Dermoscopic images of 114 histologically proven MIS were evaluated by 3 expert dermoscopists and classified into their main dermoscopic patterns. Dermoscopic features were also considered for their correlation with clinical parameters. <b><i>Results:</i></b> Eight different dermoscopic subtypes of MIS were identified: reticular grey-blue (27.2%), reticular (21.1%), multicomponent (20.2%), island (10.5%), spitzoid (7%), inverse network (6.1%), ‘net-blue globules’ (5.3%) and globular (2.6%). Clinical characteristics of lesions and patients varied according to the different dermoscopic groups. <b><i>Conclusion:</i></b> We hypothesize that the different dermoscopic subgroups of MIS correspond to lesions with a different origin and, possibly, various patterns of growth and a different biological behaviour.