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Dye‐Loaded Ferritin Nanocages for Multimodal Imaging and Photothermal Therapy

2014; Volume: 26; Issue: 37 Linguagem: Inglês

10.1002/adma.201400914

1521-4095

Peng Huang, Pengfei Rong, Albert J. Jin, Xuefeng Yan, Molly Gu Zhang, Jing Lin, Hao Hu, Zhe Wang, Xuyi Yue, Wanwan Li, Gang Niu, Wenbin Zeng, Wei Wang, Kechao Zhou, Xiaohong Chen,

Extracellular vesicles in disease

Multimodal imaging-guided photothermal therapy (PTT), for the therapy of cancer, based on a ferritin (FRT) nanocage loaded with the near-infrared dye IR820 (designated DFRT) is demonstrated. The dual roles of DFRT (in imaging and PTT) are successfully balanced by using two different excitation wavelengths: 550 nm for high quantum-yield fluorescence imaging on the one hand and 808 nm for photoacoustic imaging and PTT with high photothermal conversion efficiency on the other. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.