Atrial septal defect (secundum) associated with mitral regurgitation
1974; Elsevier BV; Volume: 34; Issue: 3 Linguagem: Inglês
10.1016/0002-9149(74)90035-6
ISSN1879-1913
AutoresKieran M. Hynes, Robert L. Frye, Robert O. Brandenburg, Dwight C. McGoon, Jack L. Titus, Emilio R. Giuliani,
Tópico(s)Cardiac tumors and thrombi
ResumoMitral regurgitation was found in 6 percent (46 patients) of all patients with a secundum atrial septal defect who were operated on during a 13 year period at the Mayo Clinic. The presence of two separate systolic murmurs, expiratory splitting of the second heart sound and evidence of overactivity of both the right and the left ventricles were the most reliable clues to the diagnosis. Nineteen of 39 patients (49 percent) had increased pulmonary arterial pressure, but only 3 patients had obstructive pulmonary vascular disease. Electrocardlographic findings rarely helped differentiate the patient who had a secundum atrial septal defect and associated mitral regurgitation from the one who had an isolated septal defect. The causes for the mitral regurgitation varied. Six patients had rheumatic valvulitis, 8 had redundant mitral valve tissue with prolapsing leaflets, 9 patients had two or more causes, and in 18, no cause for the regurgitation could be found.
Referência(s)