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FLUORESCENCE OF NAILS FROM QUINACRINE HYDROCHLORIDE

1946; American Medical Association; Volume: 131; Issue: 10 Linguagem: Inglês

10.1001/jama.1946.02870270009004

2376-8118

Robert R. Kierland,

Nail Diseases and Treatments

The accidental finding of intense fluorescence of the toenails and fingernails of persons receiving quinacrine hydrochloride (atabrine) was first noted in December 1945. This occurred when one of us (R. R. K.) was examining a patient with the Wood light and noticed a brilliant yellow-green fluorescence of the examiner's nails, as shown in the accompanying illustration. This examiner had just returned from the Southwest Pacific Theater, where he had been taking in daily doses for almost two years. The fluorescence of the so-called normal nail is much less intense than that of the atabrine nail and its color is quite different, in the normal nail being violet-blue and in the atabrine nail being yellow-green to almost white. Since then an additional 9 persons have shown this fluorescence. All of them had taken from five to twenty-one months. In no person not receiving has this fluorescence been observed.