Are double‐blind controlled trials always necessary?
1992; Wiley; Volume: 7; Issue: 1 Linguagem: Inglês
10.1002/hup.470070108
ISSN1099-1077
AutoresChris Nunn, Peter Stonier, S. Brandon,
Tópico(s)Meta-analysis and systematic reviews
ResumoHuman Psychopharmacology: Clinical and ExperimentalVolume 7, Issue 1 p. 55-61 Comment Are double-blind controlled trials always necessary? C. M. H. Nunn, C. M. H. Nunn Department of Psychiatry, Royal South Hants Hospital, Southampton, S09 4PE, UKSearch for more papers by this authorPeter D. Stonier, Peter D. Stonier Hoechst UK Ltd, Hoechst House, Salisbury Road, Hounslow, Middlesex TW4 6JH, UKSearch for more papers by this authorS. Brandon, S. Brandon University of Leicester School of Medicine, Clinical Sciences Building, Royal Infirmary, Leicester LE2 7LX, UKSearch for more papers by this author C. M. H. Nunn, C. M. H. Nunn Department of Psychiatry, Royal South Hants Hospital, Southampton, S09 4PE, UKSearch for more papers by this authorPeter D. Stonier, Peter D. Stonier Hoechst UK Ltd, Hoechst House, Salisbury Road, Hounslow, Middlesex TW4 6JH, UKSearch for more papers by this authorS. Brandon, S. Brandon University of Leicester School of Medicine, Clinical Sciences Building, Royal Infirmary, Leicester LE2 7LX, UKSearch for more papers by this author First published: January/February 1992 https://doi.org/10.1002/hup.470070108Citations: 1Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References Hamilton, M. (1982). The effect of treatment on the melancholias (depression). British Journal of Psychiatry, 140, 223–230. Isis 2 (Second International Study of Infarct Survival) Collaborative Group (1988). Randomised trial of intravenous streptokinase, or aspirin, both or neither among 17,187 cases of suspected acute myocardial infarction. Lancet, 2, 349–360. Medical Research Council Drug Trials Committee (1981). Psychological Medicine, 11, 409. Newcombe, R. G. (1987). Towards a reduction in publication bias. British Medical Journal, 295, 656–659. Nolvadex Adjuvant Trial Organisation (1983). Controlled trial of tamoxifen as an adjuvant agent in the management of early breast cancer. Lancet, 1, 257–262. Oxtoby, A., Jones, A. and Robinson, M. (1989). Is your ‘double blind’ truly double blind? British Journal of Psychiatry, 155, 700–701. Paykel, E. S. (1989). Treatment of depression. The relevance of research for clinical practice. British Journal of Psychiatry, 155, 754–763. Thomson, R. (1982). Side effects and placebo amplication. British Journal of Psychiatry, 140, 64–68. Sacks, H. S., Berrier, J., Reitman, D., Angona-Berk, V. and Chalmers, T. (1987). Metaanalysis of randomised clinical trials. New England Journal of Medicine, 316, 450–455. References Good Clinical Practice for Trials on Medicinal Products in the European Community. III/3976/33-EN Final (1990). Pharmacology and Toxicology, 67, 361–372. M. Hamilton (ed.) (1974) Lectures on the Methodology of Clinical Research, 2nd edn. Churchill Livingstone, London. I. Hindmarch and P. D. Stonier (eds) (1991). Human Psychopharmacology; Methods and Measures, vol. 3. John Wiley and Sons, Chichester. Inman, W. H. W., Rawson, R. S. B. and Wilton, L. V. (1986). Prescription-event monitoring. In: Monitoring for Drug Safety, 2nd ed., W. H. W. Inman (ed.). MPT Press, Lancaster, 213–235. R. Mann (ed.) (1987) Adverse Drug Reactions. The Scale and Nature of the Problem and the Way Forward. Parthenon Publishing Group Limited, Carnforth. Nunn, C. M. H. (1992). Are double-blind controlled trials always necessary? Human Psychopharmacology (this issue). Rawson, N. S. B., Pearce, G. L. and Inman, W. H. W. (1990). Prescription—event monitoring: methodology and recent progress. Journal of Clinical Epidemiology, 43, 509–522. F. O. Wells (ed.) (1990) Medicines: Good Research Practices. Queen's University of Belfast, Belfast. References Ackner, B. and Oldham, J. A. (1960). Insulin treatment of schizophrenia: a controlled study. Lancet, 1, 711. Anonymous (1991.) Patient compliance in therapeutic trials. Lancet, 337, 823–824. Davis, A. E., Dinitz, S. and Pasamand, B. (1972). The prevention of hospitalisation in schizophrenia, five years after an experimental programme. American Journal of Orthopsychiatry, 42, 375–388. F. N. Johnson and S. Johnson (eds) (1977). Clinical Trials. Blackwell Scientific Publications, Oxford. Klerman, G. and Cole, J. O. (1965). Clinical pharmacology of impramine and related antidepressant compounds. Pharmacological Reviews, 17, 101–141. Leff, J., Kuipes, L., Berkowitz, R. and Sturgess, D. (1985). A controlled trial of social intervention in the families of schizophrenic patients: two year follow up. British Journal of Psychiatry, 146, 594–600. Mindham, R. H., Gainol, R., Anstee, B. H. et al. (1972). Comparison of amantadine, orphenadrine and placebo in the control of phenothozyne induced Parkinsonism. Psychological Medicine, 2, 406–413. Nunn, C. M. H. (1992). Are double-blind controlled trials always necessary? Human Psychopharmacology (this issue). Citing Literature Volume7, Issue1January/February 1992Pages 55-61 ReferencesRelatedInformation
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