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BIBTEX RIS

Kojic acid biosynthesis in Aspergillus oryzae is regulated by a Zn(II)2Cys6 transcriptional activator and induced by kojic acid at the transcriptional level

2011; Elsevier BV; Volume: 112; Issue: 1 Linguagem: Inglês

10.1016/j.jbiosc.2011.03.010

ISSN

1389-1723

Autores

Junichiro Marui, Noriko Yamane, Sumiko Ohashi-Kunihiro, Tomohiro Ando, Yasunobu Terabayashi, Motoaki Sano, Shinichi Ohashi, Eiji Ohshima, Kuniharu Tachibana, Yoshitaka Higa, Marie Nishimura, Hideaki Koike, Masayuki Machida,

Tópico(s)

Microbial Natural Products and Biosynthesis

Resumo

A gene encoding the Zn(II)2Cys6 transcriptional factor is clustered with two genes involved in biosynthesis of a secondary metabolite, kojic acid (KA), in Aspergillus oryzae. We determined that the gene was essential for KA production and the transcriptional activation of KA biosynthetic genes, which were triggered by the addition of KA.

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