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Origin of the somatic cells in the rat gonad : An autoradiographic approach

1979; Elsevier BV; Volume: 19; Issue: 4B Linguagem: Inglês

10.1051/rnd

1297-9708

Horacio Merchant‐Larios, B. CENTENO-URRUIZA,

Congenital heart defects research

Gonads from rats of 11 and 12 days of gestation that had been given a pulse of 3 H-thymidine were studied at different times using autoradiographic techniques.When the animals were labeled before the formation of the gonadal blastema (11 days), the percentage of labeled cells in this structure was greater than in the coelomic epithelium and mesenchyme.However, when 3 H-thymidine was injected after the gonadal blastema was already established (12 days), very few of these cells took up the compound ; they remained in this condition until the sexual differentiation of the gonad.From this charac- teristic, which is an indication of the early differentiation of the blastemal cells, one may conclude that the seminiferous cords arise from this initial cellular line.On the other hand, there appears to be a contribution of coelomic epithelial cells during the formation of the sex cords in the ovary.