Microwave assisted convenient synthesis of quino[2,3-b][1,5]benzoxazepines
2009; Elsevier BV; Volume: 20; Issue: 5 Linguagem: Inglês
10.1016/j.cclet.2009.01.031
ISSN1878-5964
AutoresSwapnil S. Sonar, Amol H. Kategaonkar, Shivaji S. Pawar, Bapurao B. Shingate, Murlidhar S. Shingare,
Tópico(s)Multicomponent Synthesis of Heterocycles
ResumoA convenient synthesis of quino[2,3-b][1,5]benzoxazepines from substituted 2-chloroquinoline-3-carbaldehyde and 2-hydroxy aniline by using stable, non-toxic and inexpensive catalyst 1,8-diazabicyclo-undecan-7-ene (DBU)/silica gel is described. This method affords the quino[2,3-b][1,5]benzoxazepines under the influence of microwave irradiation (360 W) in solvent-free conditions within short reaction times (2–3 min), giving high yields of products (93–96%).
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