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Detection of single and mixed VOCs by smell and by sensory irritation

2004; Wiley; Volume: 14; Issue: s8 Linguagem: Inglês

10.1111/j.1600-0668.2004.00297.x

1600-0668

J. Enrique Cometto‐Muñiz, William S. Cain, Michael H. Abraham,

Indoor Air Quality and Microbial Exposure

Indoor AirVolume 14, Issue s8 p. 108-117 Detection of single and mixed VOCs by smell and by sensory irritation J. Enrique Cometto-Muñiz, J. Enrique Cometto-Muñiz Chemosensory Perception Laboratory, Department of Surgery (Otolaryngology), University of California, San Diego, La Jolla CA 92093-0957, USASearch for more papers by this authorWilliam S. Cain, William S. Cain Chemosensory Perception Laboratory, Department of Surgery (Otolaryngology), University of California, San Diego, La Jolla CA 92093-0957, USASearch for more papers by this authorMichael H. Abraham, Michael H. Abraham Department of Chemistry, University College London, 20 Gordon Street, London WC1H OAJ, UK.Search for more papers by this author J. Enrique Cometto-Muñiz, J. Enrique Cometto-Muñiz Chemosensory Perception Laboratory, Department of Surgery (Otolaryngology), University of California, San Diego, La Jolla CA 92093-0957, USASearch for more papers by this authorWilliam S. Cain, William S. Cain Chemosensory Perception Laboratory, Department of Surgery (Otolaryngology), University of California, San Diego, La Jolla CA 92093-0957, USASearch for more papers by this authorMichael H. Abraham, Michael H. Abraham Department of Chemistry, University College London, 20 Gordon Street, London WC1H OAJ, UK.Search for more papers by this author First published: 09 October 2008 https://doi.org/10.1111/j.1600-0668.2004.00297.xCitations: 62 J. Enrique Cometto-Muñiz Chemosensory Perception Laboratory, Department of Surgery (Otolaryngology), University of California, San Diego, 9500 Gilman Dr, Mail Code 0957, La Jolla, CA 92093-0957, USA Tel.: +1 858 622 5832 Fax: +1 858 458 9417 e-mail: [email protected] Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References Abraham, M.H., Andonian-Haftvan, J., Cometto-Muñiz, J.E. and Cain, W.S. (1996) An analysis of nasal irritation thresholds using a new solvation equation, Fundamental Appl. Toxicol., 31, 71– 76.DOI: 10.1006/faat.1996.0077 Abraham, M.H., Gola, J.M.R., Cometto-Muñiz, J.E. and Cain, W.S. (2001) The correlation and prediction of VOC thresholds for nasal pungency, eye irritation and odour in humans, Indoor Built Environ., 10, 252– 257.DOI: 10.1159/000049244 Abraham, M.H., Gola, J.M.R., Cometto-Muñiz, J.E. and Cain, W.S. (2002) A model for odor thresholds, Chem. Senses, 27, 95– 104.DOI: 10.1093/chemse/27.2.95 Abraham, M.H., Hassanisadi, M., Jalali-Heravi, M., Ghafourian, T., Cain, W.S. and Cometto-Muñiz, J.E. (2003) Draize rabbit eye test compatibility with eye irritation thresholds in humans: A quantitative structure-activity relationship analysis, Toxicol. Sci., 76, 384– 391.DOI: 10.1093/toxsci/kfg242 Abraham, M.H., Kumarsingh, R., Cometto-Muñiz, J.E. and Cain, W.S. (1998a) An algorithm for nasal pungency thresholds in man, Arch. Toxicol., 72, 227– 232.DOI: 10.1007/s002040050493 Abraham, M.H., Kumarsingh, R., Cometto-Muñiz, J.E. and Cain, W.S. (1998b) Draize eye scores and eye irritation thresholds in man can be combined into one quantitative structure-activity relationship, Toxicol. Vitro, 12, 403– 408.DOI: 10.1016/S0887-2333(98)00010-1 AIHA. (1989) Odor Thresholds for Chemicals with Established Occupational Health Standards, Cincinnati, Ohio, American Industrial Hygiene Association, AIHA. Aungst, J.L., Heyward, P.M., Puche, A.C., Karnup, S.V., Hayar, A., Szabo, G. and Shipley, M.T. (2003) Centre-surround inhibition among olfactory bulb glomeruli, Nature, 426, 623– 629.DOI: 10.1038/nature02185 Cain, W.S. (1989) Testing olfaction in a clinical setting, Ear, Nose Throat J., 68, 316– 328. Cain, W.S., Cometto-Muñiz, J.E. and De Wijk, R.A. (1992) Techniques in the quantitative study of human olfaction. In: M.J. Serby and K.L. Chobor, eds. Science of Olfaction. New York, Springer-Verlag, pp. 279– 308. Cometto-Muñiz, J.E. (2001) Physicochemical basis for odor and irritation potency of VOCs. In: J.D. Spengler, J. Samet and J.F. McCarthy, eds. Indoor Air Quality Handbook. New York, McGraw-Hill, pp. 20.1– 20.21. Cometto-Muñiz, J.E. and Cain, W.S. (1990) Thresholds for odor and nasal pungency, Physiol. Behav., 48, 719– 725.DOI: 10.1016/0031-9384(90)90217-R Cometto-Muñiz, J.E. and Cain, W.S. (1998) Trigeminal and olfactory sensitivity: Comparison of modalities and methods of measurement, Int. Arch. Occup. Environ. Health, 71, 105– 110.DOI: 10.1007/s004200050256 Cometto-Muñiz, J.E., Cain, W.S. and Abraham, M.H. (1998) Nasal pungency and odor of homologous aldehydes and carboxylic acids, Exp. Brain Res., 118, 180– 188.DOI: 10.1007/s002210050270 Cometto-Muñiz, J.E., Cain, W.S. and Abraham, M.H. (2003a) Dose-addition of individual odorants in the odor detection of binary mixtures, Behav. Brain Res., 138, 95– 105.DOI: 10.1016/S0166-4328(02)00234-6 Cometto-Muñiz, J.E., Cain, W.S. and Abraham, M.H. (2003b) Quantification of chemical vapors in chemosensory research, Chem. Senses, 28, 467– 477. Cometto-Muñiz, J.E., Cain, W.S. and Abraham, M.H. (2004) Chemosensory additivity in trigeminal chemoreception as reflected by detection of mixtures, Exp. Brain Res., 158, 196– 206. Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H. and Gola, J.M.R. (1999) Chemosensory detectability of 1-butanol and 2-heptanone singly and in binary mixtures, Physiol. Behav., 67, 269– 276.DOI: 10.1016/S0031-9384(99)00074-8 Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H. and Gola, J.M.R. (2001) Ocular and nasal trigeminal detection of butyl acetate and toluene presented singly and in mixtures, Toxicol. Sci., 63, 233– 244. Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H. and Gola, J.M.R. (2002) Psychometric functions for the olfactory and trigeminal detectability of butyl acetate and toluene, J. Appl. Toxicol., 22, 25– 30.DOI: 10.1002/jat.822 Cometto-Muñiz, J.E., Cain, W.S., Hiraishi, T., Abraham, M.H. and Gola, J.M.R. (2000) Comparison of two stimulus-delivery systems for measurement of nasal pungency thresholds, Chem. Senses, 25, 285– 291. Cometto-Muñiz, J.E., Cain, W.S. and Hudnell, H.K. (1997) Agonistic sensory effects of airborne chemicals in mixtures: Odor, nasal pungency, and eye irritation, Perception Psychophys., 59, 665– 674. Devos, M., Patte, F., Rouault, J., Laffort, P. and Van Gemert, L.J. (1990) Standardized Human Olfactory Thresholds. Oxford, IRL Press. Engvall, K., Norrby, C. and Norback, D. (2002) Ocular, airway, and dermal symptoms related to building dampness and odors in dwellings, Arch. Environ. Health, 57, 304– 310. Fazzalari, F.A., ed. (1978) Compilation of Odor and Taste Threshold Values Data, Philadelphia, American, Society for Testing and Materials. Feller, W. (196871) An Introduction to Probability Theory and its Applications. New York, Wiley. Franks, N.P. and Lieb, W.R. (1990) Mechanisms of general anesthesia, Environ. Health Perspectives, 87, 199– 205. Van Gemert, L.J. 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(1999) Sensory and chemical characterization of VOC emissions from building products: Impact of concentration and air velocity, Atmos. Environ., 33, 1217– 1230. Kobal, G., Van Toller, S. and Hummel, T. (1989) Is there directional smelling? Experientia, 45, 130– 132. Kostiainen, R. (1995) Volatile organic compounds in the indoor air of normal and sick houses, Atmos. Environ., 29, 693– 702. Macmillan, N.A. and Creelman, C.D. (1991) Detection Theory: a User's Guide. Cambridge, UK, Cambridge University Press. Mølhave, L., Grønkjær Jensen, J. and Larsen, S. (1991) Subjective reactions to volatile organic compounds as air pollutants, Atmospheric Environ., 25A, 1283– 1293. Rothweiler, H. and Schlatter, C. (1993) Human exposure to volatile organic compounds in indoor air—A health risk? Toxicol. Environ. Chem., 40, 93– 102. Ruth, J.H. (1986) Odor thresholds and irritation levels of several chemical substances: a review, Am. Industrial Hygiene Assoc. J., 47, A142– A151. Tsai, Y.J. and Gershwin, M.E. (2002) The sick building syndrome: what is it when it is? Comp. Ther., 28, 140– 144. Wolkoff, P. and Wilkins, C.K. (1994) Indoor VOCs from household floor dust – Comparison of headspace with desorbed VOCs – Method for VOC release determination, Indoor Air, 4, 248– 254. Citing Literature Volume14, Issues8December 2004Pages 108-117 ReferencesRelatedInformation