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Contrast-Induced Acute Kidney Injury

2016; Elsevier BV; Volume: 68; Issue: 13 Linguagem: Inglês

10.1016/j.jacc.2016.05.099

1558-3597

Peter A. McCullough, James P. Choi, Georges Feghali, Jeffrey Schussler, Robert M. Stoler, Ravi C. Vallabahn, Ankit Mehta,

Trauma, Hemostasis, Coagulopathy, Resuscitation

Coronary angiography and percutaneous intervention rely on the use of iodinated intravascular contrast for vessel and chamber imaging. Despite advancements in imaging and interventional techniques, iodinated contrast continues to pose a risk of contrast-induced acute kidney injury (CI-AKI) for a subgroup of patients at risk for this complication. There has been a consistent and graded signal of risk for associated outcomes including need for renal replacement therapy, rehospitalization, and death, according to the incidence and severity of CI-AKI. This paper reviews the epidemiology, pathophysiology, prognosis, and management of CI-AKI as it applies to the cardiac catheterization laboratory.