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Glycogen-rich clear cell carcinoma of the breast: A light and electron microscopic study

1981; Wiley; Volume: 48; Issue: 9 Linguagem: Inglês

10.1002/1097-0142(19811101)48

1097-0142

Meredith T. Hull, John B. Priest, Thomas A. Broadie, Robert C. Ransburg, Leo J. McCarthy,

Salivary Gland Tumors Diagnosis and Treatment

CancerVolume 48, Issue 9 p. 2003-2009 ArticleFree Access Glycogen-rich clear cell carcinoma of the breast: A light and electron microscopic study Meredith T. Hull MD, Corresponding Author Meredith T. Hull MD Department of Pathology, Indiana University School of Medicine and the William N. Wishard Memorial Hospital, Indianapolis, IndianaDepartment of Pathology, Indiana University Hospital, Indiana University Medical Center, Indianapolis, IN 46223===Search for more papers by this authorJohn B. Priest MD, John B. Priest MD Department of Pathology, Indiana University School of Medicine and the William N. Wishard Memorial Hospital, Indianapolis, IndianaSearch for more papers by this authorThomas A. Broadie MD, Thomas A. Broadie MD Department of Surgery, Indiana University School of Medicine and the William N. Wishard Memorial Hospital, Indianapolis, IndianaSearch for more papers by this authorRobert C. Ransburg MD, Robert C. Ransburg MD Department of Pathology, Indiana University School of Medicine and the William N. Wishard Memorial Hospital, Indianapolis, IndianaSearch for more papers by this authorLeo J. McCarthy MD, Leo J. McCarthy MD Department of Pathology, Indiana University School of Medicine and the William N. Wishard Memorial Hospital, Indianapolis, IndianaSearch for more papers by this author Meredith T. Hull MD, Corresponding Author Meredith T. Hull MD Department of Pathology, Indiana University School of Medicine and the William N. Wishard Memorial Hospital, Indianapolis, IndianaDepartment of Pathology, Indiana University Hospital, Indiana University Medical Center, Indianapolis, IN 46223===Search for more papers by this authorJohn B. Priest MD, John B. Priest MD Department of Pathology, Indiana University School of Medicine and the William N. Wishard Memorial Hospital, Indianapolis, IndianaSearch for more papers by this authorThomas A. Broadie MD, Thomas A. Broadie MD Department of Surgery, Indiana University School of Medicine and the William N. Wishard Memorial Hospital, Indianapolis, IndianaSearch for more papers by this authorRobert C. Ransburg MD, Robert C. Ransburg MD Department of Pathology, Indiana University School of Medicine and the William N. Wishard Memorial Hospital, Indianapolis, IndianaSearch for more papers by this authorLeo J. McCarthy MD, Leo J. McCarthy MD Department of Pathology, Indiana University School of Medicine and the William N. Wishard Memorial Hospital, Indianapolis, IndianaSearch for more papers by this author First published: 1 November 1981 https://doi.org/10.1002/1097-0142(19811101)48:9 3.0.CO;2-QCitations: 49AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract A glycogen-rich clear cell carcinoma arose in the breast of a 49-year-old woman. Light microscopic examination of the neoplasm revealed both intraductal papillary growth and stromal invasion. Electron microscopic examination demonstrated neoplastic cells that contained massive quantities of nonmembrane-bound particulate glycogen and that formed numerous acini. Apically, these cells formed microvilli; laterally they formed tight junctions and desmosomes. Morphologic features of this neoplasm are similar to those of the fetal breast and to some other clear cell carcinomas arising elsewhere in the body. References 1 Hull MT, Seo I, Battersby JS, Csicsko JF. Signet-ring cell carcinoma of the breast: a clinicopathologic study of 24 cases. Am J Clin Pathol 1980; 73: 31– 35. 2 Sullivan JJ, Magee HR, Donald KJ. Secretory (juvenile) carcinoma of the breast. Pathology 1977; 9: 341– 346. 3 Aboumrad MH, Horn RC, Fine G. Lipid-secreting mammary carcinoma: Report of a case associated with Paget's disease of the nipple. Cancer 1963; 16: 521– 525. 4 Tobon H, Salazar H. Ultrastructure of the human mammary gland. I. Development of the fetal gland through gestation. 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