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Atracurium and severe hepatic disease: a case report

1985; Springer Nature; Volume: 32; Issue: 2 Linguagem: Inglês

10.1007/bf03010043

0008-2856

Henry K. Gyasi, Mohamed Naguib,

Poisoning and overdose treatments

Atracurium is a new non-depolarising neuromuscular blocking agent, metabolized through Hofmann elimination. A case is presented in which a 45-year-old patient with severe liver disease showed a decreased response to atracurium. The possible causes of resistance to atracurium are discussed. We conclude that atracurium may be used in patients with severe hepatic disease.