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EFFECTS OF PROPRANOLOL ON THE RESPONSE OF HUMAN ECCRINE SWEAT GLANDS TO ACETYLCHOLINE

2006; Oxford University Press; Volume: 85; Issue: 4 Linguagem: Inglês

10.1111/j.1365-2133.1971.tb14031.x

1365-2133

Kelly Foster, J. R. Haspineall, C. L. Mollel,

Sympathectomy and Hyperhidrosis Treatments

Summary.— Propranolol had no marked effects on the acetylcholine-induced sweat response in normal subjects. The only effects were (1) a slight and transient prolongation of the secretion; (2) a very slight and transient anti-cholinergic activity. These findings do not support the existence of a β-receptor inhibitory mechanism affecting sweat gland activity as postulated by Hemels (1970).