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Myosin filaments showing a 430 Å axial repeat periodicity

1974; Elsevier BV; Volume: 82; Issue: 3 Linguagem: Inglês

10.1016/0022-2836(74)90600-7

1089-8638

Barbra L. Eaton, Frank A. Pepe,

Ion channel regulation and function

Abstract Synthetic myosin filaments with regular projections at intervals of 430 A along their entire lengths have been observed using the electron microscope. The filaments were formed following dialysis in or rapid dilution to 0.3 m -KC1, 0.01 m -imidazole or phosphate buffer, pH 7.0. It is suggested that these filaments are made up of myosin molecules staggered by 430 A.