PERFORMANCE OF THE JOUYBAN-ACREE MODEL FOR CORRELATING THE SOLUBILITY OF INDOMETHACIN AND ETHYLHEXYL TRIAZONE IN ETHYL ACETATE + ETHANOL MIXTURES
2010; Universidad de Antioquia; Volume: 17; Issue: 3 Linguagem: Inglês
10.17533/udea.vitae.7438
ISSN0121-4004
AutoresMiller A. RUIDIAZ M., Sylvia J. RODRÍGUEZ D., José R. Pedro, Diana M. CRISTANCHO B., Fleming Martínez,
Tópico(s)Chemical Thermodynamics and Molecular Structure
ResumoThis work reports the experimental volumetric properties and also the saturated solubility of indomethacin and ethylhexyl triazine in ethyl acetate + ethanol mixtures at 293.15 to 313.15 K and evaluates the validity of the Jouyban-Acree (J & A) model to correlate the solubility of these compounds in ethyl acetate + ethanol solvent mixtures. The solubility correlation is studied as a function of temperature and cosolvent composition. The J & A model requires only the experimental solubility values in the pure solvents at all the temperatures under study. The calculated values by using both compounds deviate as mean in 30% from experimental solubility values.
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