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Clonazepam in Juvenile Myoclonic Epilepsy

1989; Wiley; Volume: 30; Issue: 5 Linguagem: Inglês

10.1111/j.1528-1157.1989.tb05479.x

1528-1167

Tahir Obeid, C. P. Panayiotopoulos,

Ion Transport and Channel Regulation

We studied the efficacy of clonazepam (CZP) in control of juvenile myoclonic epilepsy (JME) in 17 patients. CZP was very effective in controlling myoclonic jerks in all patients but did not suppress generalized tonic-clonic seizures (GTCS). A disadvantage occurs because the patient is deprived of the warning jerks which presage the onset of GTCS. The circadian rhythm of the GTCS was also changed in two patients.