Portal de Periódicos da CAPES

Filaggrin: A Keratin Filament Associated Protein a

1985; Wiley; Volume: 455; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1985.tb50420.x

1749-6632

Beverly A. Dale, Katheryn A. Resing, John D. Lonsdale‐Eccles,

Biochemical and Structural Characterization

Annals of the New York Academy of SciencesVolume 455, Issue 1 p. 330-342 Filaggrin: A Keratin Filament Associated Proteina B. A. DALE, B. A. DALE Department of Periodontics, Oral Biology, Medicine/Dermatology, University of Washington, Seattle, Washington 98195Search for more papers by this authorK. A. RESING, K. A. RESING Department of Biochemistry, University of Washington, Seattle, Washington 98195Search for more papers by this authorJ. D. LONSDALE-ECCLES, J. D. LONSDALE-ECCLES Department of Periodontics, University of Washington, Seattle, Washington 98195 Present address: International Laboratory for Research in Animal Diseases, P. O. Box 30709, Nairobi, Kenya.Search for more papers by this author B. A. DALE, B. A. DALE Department of Periodontics, Oral Biology, Medicine/Dermatology, University of Washington, Seattle, Washington 98195Search for more papers by this authorK. A. RESING, K. A. RESING Department of Biochemistry, University of Washington, Seattle, Washington 98195Search for more papers by this authorJ. D. LONSDALE-ECCLES, J. D. LONSDALE-ECCLES Department of Periodontics, University of Washington, Seattle, Washington 98195 Present address: International Laboratory for Research in Animal Diseases, P. O. Box 30709, Nairobi, Kenya.Search for more papers by this author First published: October 1985 https://doi.org/10.1111/j.1749-6632.1985.tb50420.xCitations: 125 a Supported by grants from the United States Public Health Service National Institutes of Health (DE04660, DE02600, and GM15731). AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Odland, G. F. 1983. Structure of the skin. In Biochemistry and Physiology of the Skin. L. A. Goldsmith, Ed. 1: 3– 63. Oxford University Press. New York . 2 Dale, B. A., K. A. Holbrook and P. M. Steinert. 1978. Assembly of stratum corenum basic protein and keratin filaments in macrofibrils. Nature 276: 729– 731. 3 Dale, B. A., J. D. Lonsdale-Eccles and K. A. Holbrook. 1980. Stratum corneum basic protein: an interfilamentous matrix protein of epidermal keratin. In Biochemistry of Normal and Abnormal Epidermal Differentiation. I. A. Bernstein and M. Seiji, Eds.: 311– 325. University of Tokyo Press. Tokyo . 4 Ball, R. C., G. K. Walker and I. A. Bernstein. 1978. Histidine-rich proteins as molecular markers of epidermal differentiation. J. Biol. Chem. 253: 5861– 5868. 5 Scott, I. R. and C. R. Harding. 1981. Studies on the synthesis and degradation of a high molecular weight, histidine-rich phosphoprotein from mammalian epidermis. Biochim. Biophys. Acta 719: 110– 117. 6 Ramsden, M., D. Loehren and A. Balmain. 1983. Identification of a rapidly labeled 350k histidine-rich protein in neonatal mouse epidermis. Differentiation 23: 243– 249. 7 Lonsdale-Eccles, J. D., J. A. Haugen and B. A. Dale. 1980. A phosphorylated keratohyalin-derived precursor of epidermal stratum corneum basic protein. J. Biol. Chem. 255: 2235– 2238. 8 Lonsdale-Eccles, J. D., K. A. Resing, R. L. Meek and B. A. Dale. 1984. High-molecular weight precursor of epidermal filaggrin and hypothesis for its tandem repeating structure. Biochemistry 23: 1239– 1245. 9 Harding, C. R. and I. R. Scott. 1983. Histidine-rich proteins (filaggrins): structural and functional heterogeneity during epidermal differentiation. J. Mol. Biol. 170: 651– 673. 10 Woodcock-Mitchell, J., R. Eichner, W. G. Nelson and T. -T. Sun. 1982. Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies. J. Cell Biol. 95: 580– 588. 11 Dale, B. A. 1977. Purification and characterization of a basic protein from the stratum corneum of mammalian epidermis. Biochim. Biophys. Acta 491: 193– 204. 12 Steinert, P. M., J. S. Cantieri, D. C. Teller, J. D. Lonsdale-Eccles and B. A. Dale. 1981. Characterization of a class of cationic proteins that specifically interact with intermediate filaments. Proc. Natl. Acad. Sci. USA 78: 4097– 4101. 13 Resing, K. A., K. A. Walsh and B. A. Dale. 1984. Identification of two intermediates during processing of profilaggrin to filaggrin. J. Cell Biol. 99: 1372– 1378. 14 Ugel, A. R. 1971. Studies on isolated aggregating oligoribonucleoproteins of the epidermis with histochemical and morphological characteristics of keratohyalin. J. Cell Biol. 49: 405– 422. 15 Sibrack, L. A., R. H. Gray and I. A. Bernstein. 1974. Localization of the histidine-rich protein in keratohyalin: a morphologic and macromolecular marker in epidermal differentiation. J. Invest. Dermatol. 62: 394– 405. 16 Hoober, J. K. and I. A. Bernstein. 1966. Protein synthesis related to epidermal differentiation. Proc. Natl. Acad. Sci. USA 56: 594– 601. 17 Dale, B. A. and S. Y. Ling. 1979. Evidence of a precursor form of stratum corneum basic protein in rat epidermis. Biochemistry 18: 3539– 3546. 18 Lonsdale-Eccles, J. D., D. C. Teller and B. A. Dale. 1982. Characterization of a phosphorylated form of the intermediate filament-aggregating protein filaggrin. Biochemistry 21: 5940– 5948. 19 Bernstein, I. A., R. K. Brabec, B. Vadlamudi, A. K. Ohno, L. W. DeLap and R. H. Gray. 1980. Molecular markers of differentiation in the epidermis of the newborn rat. In Biochemistry of Normal and Abnormal Epidermal Differentiation. I. A. Bernstein and M. Seiji, Eds.: 421– 432. University of Tokyo Press. Tokyo . 20 Lynley, A. M. and B. A. Dale. 1983. Characterization of human epidermal filaggrin, a histidine-rich, keratin filament-aggregating protein. Biochim. Biophys. Acta 744: 28– 35. 21 Dale, B. A. and S. Y. Ling. 1979. Immunologic cross-reaction of stratum corneum basic protein and a keratohyalin granule protein. J. Invest. Dermatol. 72: 257– 261. 22 Murozuka, T., K. Fukuyama and W. L. Epstein. 1979. Immunochemical comparison of histidine-rich protein in keratohyalin granules and cornified cells. Biochim. Biophys. Acta 579: 334– 345. 23 Fukuyama, K. and W. L. Epstein. 1977. Quantitative autoradiographic studies of proteins in keratohyalin granules. In Biochemistry of Cutaneous Epidermal Differentiation. M. Seiji and I. A. Bernstein, Eds.: 253– 272. Tokyo University Press. Tokyo . 24 Holbrook, K. A., B. A. Dale, J. R. Kimball, A. M. Lynley, M. A. Hoff and T. -T. Sun. 1984. Expression of epidermal proteins during human fetal skin development. J. Invest. Dermatol. 82: 400. 25 Wang, E., J. G. Cairncross, W. K. A. Yung, E. A. Garber and R. K. H. Liem. 1983. An intermediate filament-associated protein, p 50, recognized by monoclonal antibodies. J. Cell Biol. 97: 1507– 1514. 26 Eichner, R., P. Bonitz and T. -T. Sun. 1984. Classification of epidermal keratins according to their immunoreactivity, isoelectric point, and mode of expression. J. Cell Biol. 98: 1388– 1396. 27 Moll, R., I. Moll and W. Wiest. 1983. Changes in the pattern of cytokeratin polypeptides in epidermis and hair follicles during skin development in human fetuses. Differentiation 23: 170– 178. 28 Dale, B. A. and T. -T. Sun. 1983. Filaggrin, 56.5, and 65-67kD keratins share an antigenic determinant as defined by AE2 monoclonal antibody. J. Cell Biol. 97: 228a. 29 Meek, R. L., J. D. Lonsdale-Eccles and B. A. Dale. 1983. Epidermal filaggrin is synthesized on a large messenger RNA as a high-molecular weight precursor. Biochemistry 22: 4867– 4871. 30 Resing, K. A. 1984. Structure and Processing of Profilaggrin. Ph.D. Thesis. University of Washington. Seattle, WA. 31 Steinert, P. M. 1983. Epidermal keratin: filaments and matrix. In Stratum Corneum. R. Marks and G. Plewig, Eds.: 25– 38. Springer-Verlag. Berlin . 32 Scott, I. R. 1981. Factors controlling the expressed activity of histidine ammonia-lyase in the epidermis and the resulting accumulation of urocanic acid. Biochem. J. 194: 829– 838. 33 Steinert, P. M. and W. W. Idler. 1979. Postsynthetic modification of mammalian epidermal α-keratin. Biochemistry 25: 5664– 5669. 34 Ogawa, H., A. Taneda, Y. Kanoaka and T. Sekine. 1979. The histochemical distribution of protein bound sulfhydryl groups in human epidermis by the new staining method. J. Histochem. Cytochem. 27: 942– 946. 35 Steinert, P. M., W. W. Idler and S. B. Zimmerman. 1976. Self-assembly of bovine epidermal keratin filaments in vitro. J. Mol. Biol. 108: 547– 567. Citing Literature Volume455, Issue1Intermediate FilamentsOctober 1985Pages 330-342 ReferencesRelatedInformation