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Enzyme‐Mediated Controlled Release Systems by Anchoring Peptide Sequences on Mesoporous Silica Supports

2011; Wiley; Volume: 50; Issue: 9 Linguagem: Inglês

10.1002/anie.201004133

1521-3773

Carmen Coll, Laura Mondragón, Ramón Martínez‐Máñez, Félix Sancenón, M. Dolores Marcos, Juán Soto, Pedro Amorós, Enríque Pérez‐Payá,

Advanced biosensing and bioanalysis techniques

Gated community: Peptides anchored to the surface of silica mesoporous supports by a valid procedure act as gatekeepers. In this way, "zero release" supports that selectively deliver the cargo in the presence of a suitable peptidase are obtained (see picture, red spheres: cargo, colored chains: peptides).