Artigo Revisado por pares

Melanoacanthoma

1978; Wiley; Volume: 5; Issue: 3 Linguagem: Inglês

10.1111/j.1600-0560.1978.tb00949.x

ISSN

1600-0560

Autores

Otto L. A. Schlappner, Geoff Rowden, Terence M. Phillips, Zeaur Rahim,

Tópico(s)

melanin and skin pigmentation

Resumo

Electronmicroscopic studies confirmed that melanoacanthoma is a non‐nevoid elevated epithelial tumor composed of keratinocytes of both basaloid and spinous differentiation and of large dentritic melanocytes. The block in transfer of pigment from melanocytes to keratinocytes was found not to be complete. Langerhans cells, present in all the malpighian layers were normal in morphology. Immunofluorescent studies and an immunoprecipitin assay also showed our patient's melanoacanthoma not to be related to malignant melanoma.

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