Artigo Revisado por pares

6610 POSTER Safety of bevacizumab treatment in non-small cell lung cancer (NSCLC) subjects receiving full-dose anti-coagulation (FDAC) treated on protocol BO17704

2007; Elsevier BV; Volume: 5; Issue: 4 Linguagem: Inglês

10.1016/s1359-6349(07)71438-6

ISSN

1878-1217

Autores

Natasha B. Leighl, Jaafar Bennouna, H Kuo, B. Szima, Maya Gottfried, A. Kunitsyn, José Trigo, G. C. Chang, Jan Cosaert, Martin Reck,

Tópico(s)

Neonatal Respiratory Health Research

Resumo

To assess the benefits of a chemoprophylaxis program based on screening women for group B streptococcus (GBS) infection between 30 and 32 weeks of pregnancy in a population with a high rate of premature births.From 1995 to 2011, 24 950 women were screened for GBS infection between 30 and 32 weeks of pregnancy at Markusovszky Teaching Hospital, Szombathely, Hungary. Those who tested positive, and those who tested negative but were at risk of infecting their newborns, underwent intrapartum prophylaxis. Neonatal outcomes were compared with those of a historical cohort that underwent no screening or treatment, and with those published in CDC/ACOG guidelines recommending screening closer to term.There were 63 infected newborns (0.2%) in the study cohort, and 1 of 8 with sepsis died. There were 149 infected newborns (0.7%) in the historical cohort, and 29 of 31 with sepsis died.Screening women early in a population with a high rate of premature births may simplify preterm labor management. It results, however, in a higher incidence of early onset neonatal GBS disease than when screening is done closer to term.

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