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Oral erosive lichen planus with epidermolytic hyperkeratosis during interferon alfa-2b therapy for chronic hepatitis C virus infection

1997; Elsevier BV; Volume: 36; Issue: 6 Linguagem: Inglês

10.1016/s0190-9622(97)80296-4

1097-6787

Todd Schlesinger, Charles Camisa, J. Douglas Gay, Wilma F. Bergfeld,

Infectious Diseases and Mycology

mal keratinization--aU features reminiscent of the outer root sheath. 11-13 In addition, cytologic and architectural evidence of malignancy should be present. It is not known whether trichilemmomal carcinoma can evolve from a preexisting tdcholemmoma or whether de n o v o occurrence is more the rule. 14 Trichilemmomal carcinoma can be locally aggressive, but metastases appear to be rare. 15 We suggest that, once the diagnosis o f Cowden ' s disease is established, routine biopsy of facial Trichilemmomas is unn~essary. However, biopsy should be performed on any changing or atypical facial lesion.