Novel structure of the cellular mannan of the pathogenic yeast Candida krusei
1988; Elsevier BV; Volume: 184; Linguagem: Inglês
10.1016/0008-6215(88)80015-6
ISSN1873-426X
AutoresGrigorij Kogan, Viliam Pavliak, J. Šandula, L. Masler,
Tópico(s)Antifungal resistance and susceptibility
ResumoOn the basis of methylation analysis, 13C- and 1H-n.m.r. spectroscopic data, and the results of immunological methods, a new structure for the cell-wall α-d-mannan of the pathogenic yeast Candida krusei is proposed. In contrast to the α-d-mannans of other pathogenic yeasts of the Candida species, which have (1→6)-linked main chains and many (1→2)- and/or (1→3)-linked side chains, the C. krusei mannan is lightly branched and contains (1→2) and (1→6) linkages in the ratio 3:1.
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