National General Practice Study of Epilepsy: recurrence after a first seizure
1990; Elsevier BV; Volume: 336; Issue: 8726 Linguagem: Inglês
10.1016/0140-6736(90)92960-p
ISSN1474-547X
AutoresY Hart, Josemir W. Sander, SD Shorvon, A.L. Johnson,
Tópico(s)Neonatal and fetal brain pathology
ResumoIn the National General Practice Study of Epilepsy 564 patients classified as having definite seizures have been followed up for 2-4 years. 67% (95% confidence interval 63-71%) had a recurrence within 12 months of the first seizure, and 78% (74-81%) had a recurrence within 36 months. Seizures associated with a neurological deficit presumed present at birth had a high rate of recurrence (100% by 12 months), whereas seizures that occurred within 3 months of an acute insult to the brain, such as head injury or stroke, or in the context of an acute precipitant such as alcohol, carried a much lower risk of recurrence (40% [29-51%] by 12 months). Other factors affecting the risk of recurrence were age-the highest risk being for patients under the age of 16 (83% [77-89%] by 36 months) or over the age of 59 (83% [76-90%] by 36 months-and type of first seizure-the risk of recurrence being much higher for patients with simple partial or complex partial seizures (94% [90-99%] by 36 months) than for those with generalised tonic clonic seizures (72% [67-77%] by 36 months).
Referência(s)