
SPR: Uma nova ferramenta para biossensores
2003; Brazilian Chemical Society; Volume: 26; Issue: 1 Linguagem: Inglês
10.1590/s0100-40422003000100017
ISSN1678-7064
AutoresRosângela M. de Carvalho, Susanne Rath, Lauro T. Kubota,
Tópico(s)Analytical Chemistry and Sensors
ResumoSPR -NEW TOOL FOR BIOSENSORS.This paper reviewed the development and theoretical aspects of surface plasmon ressonance (SPR) technique and discusses this powerful sensor technology in the development of biosensors, as well as for the investigation of biological interactions and clinical assays.The SPR has been proven to be a valuable tool to investigate dynamic processes, such as adsorption, degradation, determination of dieletric properties, association/dissociation kinetics, affinity constants of specific ligand-ligate interactions, allowing real-time analysis at almost any surface.The SPR as a complementary technique alongside electrochemical methods is also presented.
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