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fMRI/EEG in paroxysmal activity elicited by elimination of central vision and fixation

2002; Lippincott Williams & Wilkins; Volume: 58; Issue: 6 Linguagem: Inglês

10.1212/wnl.58.6.976

1526-632X

Gian Domenico Iannetti, Carlo Di Bonaventura, Patrizià Pantano, Anna Teresa Giallonardo, Pantaleo Romanelli, L. Bozzao, M. Manfredi, Gianfranco Ricci,

Advanced Neuroimaging Techniques and Applications

Using functional MRI (fMRI) with concurrent EEG monitoring the authors studied cortical activation associated with epileptiform discharges in three patients with fixation-off sensitivity. The EEG paroxysmal activity elicited by eliminating central vision correlated significantly with an increased blood oxygen level-dependent signal in the extrastriate cortex (Brodmann areas 19 and 37). fMRI provides a unique opportunity for localizing precisely the cortical areas generating paroxysmal activity in patients with fixation-off sensitivity.