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BIBTEX RIS

Opioid activity of a peptide, beta-lipotropin-(61-91), derived from beta-lipotropin.

1976; National Academy of Sciences; Volume: 73; Issue: 6 Linguagem: Inglês

10.1073/pnas.73.6.1821

ISSN

1091-6490

Autores

Brian M. Cox, A Goldstein, Chernov Hi,

Tópico(s)

Regulation of Appetite and Obesity

Resumo

The pituitary peptide beta-lipotropin displays essentially no opoid activity in a preparation of guinea pig ileum or in the opiate receptor binding assay. However, a fragment, beta-lipotropin-(61-91), with the enkephalin sequence (Tyr-Gly-Gly-Phe-Met) at its NH2-terminus, has typical opioid effects in these two assays.

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