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Characterization of the Adjuvant Effect of IL‐12 and Efficacy of IL‐12 Inhibitors in Type II Collagen‐Induced Arthritisa

1996; Wiley; Volume: 795; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1996.tb52672.x

1749-6632

Tieno Germann, Henry Hess, Jacek Szeliga, Erwin Rüde,

Immunotherapy and Immune Responses

Annals of the New York Academy of SciencesVolume 795, Issue 1 p. 227-240 Characterization of the Adjuvant Effect of IL-12 and Efficacy of IL-12 Inhibitors in Type II Collagen-Induced Arthritisa TIENO GERMANN, TIENO GERMANN Universität Mainz, Institut für Immunologic, Obere Zahlbacher Straβe 67, 55101 Mainz, GermanySearch for more papers by this authorHENRY HESS, HENRY HESS Universität Mainz, Institut für Immunologic, Obere Zahlbacher Straβe 67, 55101 Mainz, GermanySearch for more papers by this authorJACEK SZELIGA, JACEK SZELIGA Universität Mainz, Institut für Immunologic, Obere Zahlbacher Straβe 67, 55101 Mainz, GermanySearch for more papers by this authorERWIN RÜDE, ERWIN RÜDE Universität Mainz, Institut für Immunologic, Obere Zahlbacher Straβe 67, 55101 Mainz, GermanySearch for more papers by this author TIENO GERMANN, TIENO GERMANN Universität Mainz, Institut für Immunologic, Obere Zahlbacher Straβe 67, 55101 Mainz, GermanySearch for more papers by this authorHENRY HESS, HENRY HESS Universität Mainz, Institut für Immunologic, Obere Zahlbacher Straβe 67, 55101 Mainz, GermanySearch for more papers by this authorJACEK SZELIGA, JACEK SZELIGA Universität Mainz, Institut für Immunologic, Obere Zahlbacher Straβe 67, 55101 Mainz, GermanySearch for more papers by this authorERWIN RÜDE, ERWIN RÜDE Universität Mainz, Institut für Immunologic, Obere Zahlbacher Straβe 67, 55101 Mainz, GermanySearch for more papers by this author First published: October 1996 https://doi.org/10.1111/j.1749-6632.1996.tb52672.xCitations: 28 a This work was supported by the Deutsche Forschungsgemeinschaft, Sonderforschungs-bereich 311, and a DFG grant to Jacek Szeliga. 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Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in nod mice. J. Exp. Med. 181: 817– 821. 55 Ogata, L. C., C. Reilly, L. A. M. Marconi & D. Lo. 1995. Anti-1L-12 antibody can prevent autoimmune diabetes in an adoptive transfer murine model. J. Cell. Biochem. Suppl. 21A(C2-463): 150. 56 Neurath, M. F., I. Fuss, B. L. Kelsall, E. Stüber & W. Strober. 1995. Antibodies to IL-12 abrogate established granulomatous colitis in mice. J. Exp. Med. 182: 1281– 1290. Citing Literature Volume795, Issue1Interleukin 12: Cellular and Molecular Immunology of an Important Regulatory CytokineOctober 1996Pages 227-240 ReferencesRelatedInformation