Post hoc analysis: use and dangers in perspective
1996; Lippincott Williams & Wilkins; Volume: 14; Issue: Supplement 2 Linguagem: Inglês
10.1097/00004872-199609002-00006
ISSN1473-5598
Autores Tópico(s)Metabolomics and Mass Spectrometry Studies
ResumoDangers and advantages of post hoc analysis Post hoc analysis is of major importance in the generation of hypotheses. However, the hypothesis is created by the analysis and has not been proved by any 'experiment'. In some circumstances the conclusion derived from a post hoc analysis is entirely appropriate. For example, it was the only method used by Crick and Watson for determining the structure of DNA. In other circumstances, however, the results will be misleading. Weed for caution with interpretation The results of a post hoc analysis should be viewed with considerable scepticism and, in advance of confirmation by other appropriately designed prospective
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