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Enzyme Promotes the Hydrogelation from a Hydrophobic Small Molecule

2009; American Chemical Society; Volume: 131; Issue: 32 Linguagem: Inglês

10.1021/ja9042142

1943-2984

Jie Gao, Huaimin Wang, Ling Wang, Jingyu Wang, Deling Kong, Zhimou Yang,

Hydrogels: synthesis, properties, applications

We report in this paper that an enzymatic reaction can be used as the sole mechanism for forming supramolecular hydrogels that have good stability in aqueous solutions at room temperature. The gels are two-component hydrogels that are mainly formed by hydrophobic compound 2 and doped with hydrophilic compound 1. They were formed by an enzymatic process that produces hydrophobic 2 in homogeneous modes and assists the formation of three-dimensional networks. We have characterized the morphologies of the gels with scanning electron microscopy and dark-field transmission electron microscopy, collected fluorescence data to monitor the gelation process, and proposed a possible mechanism to explain the formation of the gels.