Electrophysiological investigations of the pigeon iris neuromuscular junctions
1969; Pergamon Press; Volume: 29; Issue: 1 Linguagem: Inglês
10.1016/0010-406x(69)91725-3
ISSN1879-3029
Autores Tópico(s)Photoreceptor and optogenetics research
Resumo1. Evoked and spontaneous junctional potentials (s.j.p.s) were recorded intracellularly. 2. Nerve stimulation produced action potentials in some cells; in others graded junctional potentials were evoked. 3. S.j.p.s with variable time course and amplitude were observed. 4. The junctional potentials were built up from all-or-none quanta similar to s.j.p.s. These responses were blocked by curare and not by atropine. 5. With repetitive nerve stimulation muscle action potentials failed and the membrane remained depolarized by junctional activity. 6. Action potentials elicited after single stimulation indicated that these fibres could respond with a “twitch”. Multiple innervation and maintained depolarization during prolonged stimulation suggested that these fibres also could be operated tonically.
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