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Patterns of Peptides and Protein-Associated-Peptide Complexes in Psychiatric Disorders

1980; Cambridge University Press; Volume: 136; Issue: 1 Linguagem: Inglês

10.1192/bjp.136.1.59

1472-1465

Olav Trygstad, K. L. Reichelt, Irene Foss, Paul D. Edminson, Gry Anette Sælid, Jon Bremer, Kjell Hole, Harald Ørbeck, J.H. Johansen, J. B. B⊘ler, Kirsten Titlestad, P. K. Opstad,

Chemical Synthesis and Analysis

Peptidic neurones may be considered as multisignal intergrators and transducers. When formation or release of peptide outstrips genetically determined breakdown capacity, overflow of peptides to the body fluids and urine may be expected. In this paper, pathological urinary chromatographic patterns of peptides are shown for genetic, functional and mixed disorders. Part symptoms of the disorders may be induced with the biologically isolated and purified peptides as well as with chemically synthesized peptides.