Revisão Acesso aberto Revisado por pares

Aspirin and other antiplatelet agents in the secondary and primary prevention of cardiovascular disease.

1989; Lippincott Williams & Wilkins; Volume: 80; Issue: 4 Linguagem: Inglês

10.1161/01.cir.80.4.749

ISSN

1524-4539

Autores

Charles H. Hennekens, Julie E. Buring, Peter Sandercock, R Collins, Richard Peto,

Tópico(s)

Inflammatory mediators and NSAID effects

Resumo

HomeCirculationVol. 80, No. 4Aspirin and other antiplatelet agents in the secondary and primary prevention of cardiovascular disease. Free AccessAbstractPDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessAbstractPDF/EPUBAspirin and other antiplatelet agents in the secondary and primary prevention of cardiovascular disease. C H Hennekens, J E Buring, P Sandercock, R Collins and R Peto C H HennekensC H Hennekens Department of Medicine, Harvard Medical School, Boston, Massachusetts. , J E BuringJ E Buring Department of Medicine, Harvard Medical School, Boston, Massachusetts. , P SandercockP Sandercock Department of Medicine, Harvard Medical School, Boston, Massachusetts. , R CollinsR Collins Department of Medicine, Harvard Medical School, Boston, Massachusetts. and R PetoR Peto Department of Medicine, Harvard Medical School, Boston, Massachusetts. Originally published1 Oct 1989https://doi.org/10.1161/01.CIR.80.4.749Circulation. 1989;80:749–756 Previous Back to top Next FiguresReferencesRelatedDetailsCited By Elshafei M, Imam Y, Mohamed M, AlSaud A, Ahmed M, Obeidat K, Saeid R, Ali M, Abdallah I, Parray A and Danjuma M (2020) An investigation into the impact of enteric coated of aspirin in patients with newly diagnosed ischemic stroke (ECASIS), Medicine, 10.1097/MD.0000000000020307, 99:20, (e20307) Bach R (2019) Adjunctive Pharmacologic Therapies in Acute Myocardial Infarction Cardiac Intensive Care, 10.1016/B978-0-323-52993-8.00012-6, (117-138.e7), . Raber I, McCarthy C, Vaduganathan M, Bhatt D, Wood D, Cleland J, Blumenthal R and McEvoy J (2019) The rise and fall of aspirin in the primary prevention of cardiovascular disease, The Lancet, 10.1016/S0140-6736(19)30541-0, 393:10186, (2155-2167), Online publication date: 1-May-2019. Moya-Garzón M, Martín Higueras C, Peñalver P, Romera M, Fernandes M, Franco-Montalbán F, Gómez-Vidal J, Salido E and Díaz-Gavilán M (2018) Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1, Journal of Medicinal Chemistry, 10.1021/acs.jmedchem.8b00399, 61:16, (7144-7167), Online publication date: 23-Aug-2018. Chunduri S, Folstad J and Vachharajani T (2017) Antithrombotic therapy in end-stage renal disease, Hemodialysis International, 10.1111/hdi.12571, 21:4, (453-471), Online publication date: 1-Oct-2017. Luchessi A, Concheiro M, Germano J, Silbiger V, Bortolin R, Cruz A, Quintela O, Brion M, Carracedo A, Iñiguez A, Bravo M, López-Rivadulla M, Hirata R, Sousa A and Hirata M (2017) ABCC3 Polymorphisms and mRNA Expression Influence the Concentration of a Carboxylic Acid Metabolite in Patients on Clopidogrel and Aspirin Therapy , Basic & Clinical Pharmacology & Toxicology, 10.1111/bcpt.12703, 120:5, (466-474), Online publication date: 1-May-2017. Serebruany V and Golukhova E (2017) Aspirin in the elderly — tailored approaches ahead?, Nature Reviews Cardiology, 10.1038/nrcardio.2017.117, 14:10, (571-572), Online publication date: 1-Oct-2017. (2016) Acetylsalicylic acid Meyler's Side Effects of Drugs, 10.1016/B978-0-444-53717-1.00218-3, (26-52), . Pereira M, Lopes-Conceição L, Bennett K, Dias P, Laszczynska O, Lunet N and Azevedo A (2016) Trends in pharmacological therapy following an acute coronary syndrome in Portugal, Journal of Cardiovascular Medicine, 10.2459/JCM.0000000000000258, 17:9, (639-646), Online publication date: 1-Sep-2016. Yang L, Zhao P, Zhao J, Wang J, Shi L and Wang X (2016) Effects of ezetimibe and anticoagulant combined therapy on progressing stroke: a randomized, placebo-controlled study, Journal of Neurology, 10.1007/s00415-016-8283-0, 263:12, (2438-2445), Online publication date: 1-Dec-2016. Ding B, Xu Z, Qian C, Jiang F, Ding X, Ruan Y, Ding Z and Fan Y (2015) Antiplatelet Aggregation and Antithrombosis Efficiency of Peptides in the Snake Venom of Deinagkistrodon acutus : Isolation, Identification, and Evaluation , Evidence-Based Complementary and Alternative Medicine, 10.1155/2015/412841, 2015, (1-6), . Friedman L, Furberg C, DeMets D, Reboussin D and Granger C (2015) Issues in Data Analysis Fundamentals of Clinical Trials, 10.1007/978-3-319-18539-2_18, (403-462), . Kamble P, Litvinov D, Aluganti Narasimhulu C, Jiang X and Parthasarathy S (2015) Aspirin may influence cellular energy status, European Journal of Pharmacology, 10.1016/j.ejphar.2014.12.020, 749, (12-19), Online publication date: 1-Feb-2015. Ruparelia N (2015) Role of coronary physiology in the contemporary management of coronary artery disease, World Journal of Clinical Cases, 10.12998/wjcc.v3.i2.148, 3:2, (148), . Li J, Jian Z, Song M, Guo W, Chen G, Lu W, Qian D, Ouyang J, Yu J, Hu H, Jin J, Wu X and Huang L (2013) Tailored antiplatelet therapy and clinical adverse outcomes, Heart, 10.1136/heartjnl-2013-304461, 100:1, (41-46), Online publication date: 1-Jan-2014. Higuchi T, Iwakiri R, Hara M, Shimoda R, Sakata Y, Nakayama A, Nio K, Yamaguchi S, Yamaguchi D, Watanabe A, Akutagawa T, Sakata H and Fujimoto K (2014) Low-dose Aspirin and Comorbidities are Significantly Related to Bleeding Peptic Ulcers in Elderly Patients Compared with Nonelderly Patients in Japan, Internal Medicine, 10.2169/internalmedicine.53.0603, 53:5, (367-373), . Dollery C (2014) Lost in Translation (LiT): IUPHAR Review 6, British Journal of Pharmacology, 10.1111/bph.12580, 171:9, (2269-2290), Online publication date: 1-May-2014. Elwood P, Almonte M and Mustafa M (2012) Is There Enough Evidence for Aspirin in High-Risk Groups?, Current Colorectal Cancer Reports, 10.1007/s11888-012-0149-y, 9:1, (9-16), Online publication date: 1-Mar-2013. Luchessi A, Silbiger V, Hirata R, Lima-Neto L, Cavichioli D, Iñiguez A, Bravo M, Bastos G, Sousa A, Brión M, Carracedo A and Hirata M (2013) Pharmacogenomics of anti-platelet therapy focused on peripheral blood cells of coronary arterial disease patients, Clinica Chimica Acta, 10.1016/j.cca.2013.06.021, 425, (9-17), Online publication date: 1-Oct-2013. Nussbaumerová B and Rosolová H (2013) Current opinion on aspirin in primary prevention of atherosclerotic cardiovascular diseases. Is there any difference between diabetic and non-diabetic patients?, Cor et Vasa, 10.1016/j.crvasa.2012.11.019, 55:2, (e190-e195), Online publication date: 1-Apr-2013. Akyazi I, Eraslan E, Gülçubuk A, Ekiz E, Çırakli Z, Haktanir D, Bala D, Özkurt M, Matur E and Özcan M (2013) Long-term aspirin pretreatment in the prevention of cerulein-induced acute pancreatitis in rats, World Journal of Gastroenterology, 10.3748/wjg.v19.i19.2894, 19:19, (2894-2903), Online publication date: 21-May-2013. Mullangi R, Sharma K and Srinivas N (2012) Review of HPLC methods and HPLC methods with mass spectrometric detection for direct determination of aspirin with its metabolite(s) in various biological matrices, Biomedical Chromatography, 10.1002/bmc.2694, (n/a-n/a), Online publication date: 1-Jan-2012. Thibodeau J, Mishkin J, Patel P, Kaiser P, Ayers C, Mammen P, Markham D, Ring W, Peltz M and Drazner M (2012) Sirolimus use and incidence of venous thromboembolism in cardiac transplant recipients, Clinical Transplantation, 10.1111/j.1399-0012.2012.01677.x, 26:6, (953-959), Online publication date: 1-Nov-2012. Singh K, Salam A, Devarajan R, Patel A and Prabhakaran D (2012) Polypill (fixed-dose combination) in the prevention of cardiovascular disease: rationale and clinical data, Clinical Investigation, 10.4155/cli.12.127, 2:12, (1213-1229), Online publication date: 1-Dec-2012. Tofler G, O'Farrell A and Buckley T (2011) Psychological Triggers for Plaque Rupture Stress and Cardiovascular Disease, 10.1007/978-1-84882-419-5_9, (151-168), . Li K, Wang H, Cheng L, Zhu H, Wang M and Wang S (2011) The protective effect of salicylic acid on lysozyme against riboflavin-mediated photooxidation, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 10.1016/j.saa.2010.12.008, 79:1, (1-5), Online publication date: 1-Jun-2011. Spitz M, Caporaso N and Freedman A (2011) Epidemiology—Found in Translation, Cancer Discovery, 10.1158/2159-8274.CD-11-0042, 1:1, (21-22), Online publication date: 1-Jun-2011. Cheng C, Chen C, Kuan P, Lei M, Liau C, Ueng K, Wu C and Lai W (2010) The Causes and Outcomes of Inadequate Implementation of Existing Guidelines for Antiplatelet Treatment in Patients With Acute Coronary Syndrome: The Experience From Taiwan Acute Coronary Syndrome Descriptive Registry (T-ACCORD Registry), Clinical Cardiology, 10.1002/clc.20730, 33:6, (E40-E48), Online publication date: 1-Jun-2010. Man J, Tymchak W and Jugdutt B (2010) Adjunctive Pharmacologic Therapies in Acute Myocardial Infarction Cardiac Intensive Care, 10.1016/B978-1-4160-3773-6.10013-8, (145-182), . Friedman L, Furberg C and DeMets D (2010) Issues in Data Analysis Fundamentals of Clinical Trials, 10.1007/978-1-4419-1586-3_17, (345-398), . Razzouk L, Mathew V, Lennon R, Aneja A, Mozes J, Wiste H, Muntner P, Chesebro J and Farkouh M (2010) Aspirin Use Is Associated With an Improved Long-Term Survival in an Unselected Population Presenting With Unstable Angina, Clinical Cardiology, 10.1002/clc.20769, 33:9, (553-558) Hebert P, Schneider W and Hennekens C (2009) Use of Aspirin Among Diabetics in the Primary Prevention of Cardiovascular Disease: Need For Reliable Randomized Evidence and Astute Clinical Judgment, Journal of General Internal Medicine, 10.1007/s11606-009-1095-5, 24:11, (1248-1250), Online publication date: 1-Nov-2009. Xu X, Koetzner L, Boulet J, Maselli H, Beyenhof J and Grover G (2009) Rapid and sensitive determination of acetylsalicylic acid and salicylic acid in plasma using liquid chromatography-tandem mass spectrometry: application to pharmacokinetic study, Biomedical Chromatography, 10.1002/bmc.1209, 23:9, (973-979), Online publication date: 1-Sep-2009. Cho H, Kittaka R, Abdou A, Kim M, Kim H, Lee D and Park H (2009) Inhibitory effects of oligopeptides from hen egg white on both human platelet aggregation and blood coagulation, Archives of Pharmacal Research, 10.1007/s12272-009-1618-y, 32:6, (945-953), Online publication date: 1-Jun-2009. Nakayama M, Iwakiri R, Hara M, Ootani H, Shimoda R, Tsunada S, Sakata H and Fujimoto K (2009) Low-dose aspirin is a prominent cause of bleeding ulcers in patients who underwent emergency endoscopy, Journal of Gastroenterology, 10.1007/s00535-009-0074-2, 44:9, (912-918), Online publication date: 1-Sep-2009. (2009) ANTICOAGULANTS, THROMBOLYTIC AGENTS, AND ANTI-PLATELET DRUGS Meyler's Side Effects of Cardiovascular Drugs, 10.1016/B978-0-444-53268-8.50008-9, (449-556), . Bae S, Seo K, Jung E, Kim H, Yeo C, Shon J, Park K, Liu K and Shin J (2008) Determination of acetylsalicylic acid and its major metabolite, salicylic acid, in human plasma using liquid chromatography–tandem mass spectrometry: application to pharmacokinetic study of Astrix® in Korean healthy volunteers, Biomedical Chromatography, 10.1002/bmc.973, 22:6, (590-595), Online publication date: 1-Jun-2008. ABRAHAM N, CASTILLO D and HARTMAN C (2008) National mortality following upper gastrointestinal or cardiovascular events in older veterans with recent nonsteroidal anti-inflammatory drug use, Alimentary Pharmacology & Therapeutics, 10.1111/j.1365-2036.2008.03706.x, 28:1, (97-106) Kubota N, Kasai T, Miyauchi K, Njaman W, Kajimoto K, Akimoto Y, Kojima T, Yokoyama K, Kurata T and Daida H (2008) Therapy with statins and aspirin enhances long-term outcome of percutaneous coronary intervention, Heart and Vessels, 10.1007/s00380-007-1007-8, 23:1, (35-39), Online publication date: 1-Jan-2008. Iwakiri R and Fujimoto K (2008) Roles of NSAIDs and aspirin in bleeding peptic ulcers, Clinical Journal of Gastroenterology, 10.1007/s12328-008-0011-6, 1:2, (33-39), Online publication date: 1-Jun-2008. Khella S and Bleicher M (2007) Stroke and Its Prevention in Chronic Kidney Disease, Clinical Journal of the American Society of Nephrology, 10.2215/CJN.04341206, 2:6, (1343-1351), Online publication date: 1-Nov-2007. Njaman W, Miyauchi K, Kasai T, Kurata T, Satoh H, Ohta H, Okazaki S, Yokoyama K, Kojima T, Akimoto Y and Daida H (2006) Impact of Aspirin Treatment on Long-Term Outcome (Over 10Years) After Percutaneous Coronary Intervention, International Heart Journal, 10.1536/ihj.47.37, 47:1, (37-45), . Ajani U, Ford E, Greenland K, Giles W and Mokdad A (2006) Aspirin Use Among U.S. Adults, American Journal of Preventive Medicine, 10.1016/j.amepre.2005.08.042, 30:1, (74-77), Online publication date: 1-Jan-2006. Hennekens C, Sechenova O, Hollar D and Serebruany V (2016) Dose of Aspirin in the Treatment and Prevention of Cardiovascular Disease: Current and Future Directions, Journal of Cardiovascular Pharmacology and Therapeutics, 10.1177/1074248406292263, 11:3, (170-176), Online publication date: 1-Sep-2006. (2006) Acetylsalicylic acid Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, 10.1016/B0-44-451005-2/01197-9, (15-29), . Maalej N, Osman H, Shanmuganayagam D, Shebuski R and Folts J (2005) Antithrombotic Properties of the Thromboxane A2/Prostaglandin H2 Receptor Antagonist S18886 on Prevention of Platelet-Dependent Cyclic Flow Reductions in Dogs, Journal of Cardiovascular Pharmacology, 10.1097/01.fjc.0000157439.49612.83, 45:5, (389-395), Online publication date: 1-May-2005. Tofler G, Massaro J, Levy D, Mittleman M, Sutherland P, Lipinska I, Muller J and D'Agostino R (2005) Relation of the Prothrombotic State to Increasing Age (from the Framingham Offspring Study), The American Journal of Cardiology, 10.1016/j.amjcard.2005.06.072, 96:9, (1280-1283), Online publication date: 1-Nov-2005. Kong D (2004) Aspirin in Cardiovascular Disorders, American Journal of Cardiovascular Drugs, 10.2165/00129784-200404030-00002, 4:3, (151-158), . Shields T and Hennekens C (2004) Management of metabolic syndrome: aspirin, Endocrinology and Metabolism Clinics of North America, 10.1016/j.ecl.2004.03.015, 33:3, (577-593), Online publication date: 1-Sep-2004. Williams A and Hennekens C (2005) The role of aspirin in cardiovascular diseases – forgotten benefits?, Expert Opinion on Pharmacotherapy, 10.1517/14656566.5.1.109, 5:1, (109-115), Online publication date: 1-Jan-2004. Hennekens C, Knatterud G and Pfeffer M (2004) Use of Aspirin to Reduce Risks of Cardiovascular Disease in Patients With Diabetes, Diabetes Care, 10.2337/diacare.27.11.2752, 27:11, (2752-2754), Online publication date: 1-Nov-2004. Meir K, Leitersdorf E and Hennekens C (2003) Inflammation in atherosclerosis: causal or casual? The need for randomized trials, American Heart Journal, 10.1016/S0002-8703(03)00226-6, 146:2, (199-202), Online publication date: 1-Aug-2003. Harjai K, Solis S, Prasad A and Loupe J (2003) Use of aspirin in conjunction with angiotensin-converting enzyme inhibitors does not worsen long-term survival in heart failure, International Journal of Cardiology, 10.1016/S0167-5273(02)00401-1, 88:2-3, (207-214), Online publication date: 1-Apr-2003. Monroe V, Kerensky R, Rivera E, Smith K and Pepine C (2003) Pharmacologic plaque passivation for the reduction of recurrent cardiac events in acute coronary syndromes, Journal of the American College of Cardiology, 10.1016/S0735-1097(02)02774-2, 41:4, (S23-S30), Online publication date: 1-Feb-2003. Yasutake M, Kunimi T, Sato N, Yokoyama H, Sasaki Y, Kusama Y, Hata N, Takayama M, Munakata K, Kishida H, Takano T and Hayakawa H (2002) Effects of a Single Oral Dose of Cilostazol on Epicardial Coronary Arteries and Hemodynamics in Humans., Circulation Journal, 10.1253/circj.66.241, 66:3, (241-246), . Mehta P (2002) Aspirin in the prophylaxis of coronary artery disease, Current Opinion in Cardiology, 10.1097/00001573-200209000-00017, 17:5, (552-558), Online publication date: 1-Sep-2002. Huang F, Xiu Q, Sun J and Hong E (2002) Anti-Platelet and Anti-Thrombotic Effects of Triacetylshikimic Acid in Rats, Journal of Cardiovascular Pharmacology, 10.1097/00005344-200202000-00013, 39:2, (262-270), Online publication date: 1-Feb-2002. Signorello L, McLaughlin J, Lipworth L, Friis S, S??rensen H and Blot W (2002) Confounding by Indication in Epidemiologic Studies of Commonly Used Analgesics, American Journal of Therapeutics, 10.1097/00045391-200205000-00005, 9:3, (199-205), Online publication date: 1-May-2002. Hebert P, Pfeffer M and Hennekens C (2016) Use of Statins and Aspirin to Reduce Risks of Cardiovascular Disease, Journal of Cardiovascular Pharmacology and Therapeutics, 10.1177/107424840200700203, 7:2, (77-80), Online publication date: 1-Jun-2002. Willoughby S, Holmes A and Loscalzo J (2016) Platelets and Cardiovascular Disease, European Journal of Cardiovascular Nursing, 10.1016/S1474-51510200038-5, 1:4, (273-288), Online publication date: 1-Dec-2002. Reed J (2002) Cranberry Flavonoids, Atherosclerosis and Cardiovascular Health, Critical Reviews in Food Science and Nutrition, 10.1080/10408390209351919, 42:sup3, (301-316), Online publication date: 1-Jan-2002. Feldman M, Cryer B, Rushin K and Betancourt J (2016) A Comparison of Every-Third-Day Versus Daily Low-Dose Aspirin Therapy on Serum Thromboxane Concentrations in Healthy Men and Women, Clinical and Applied Thrombosis/Hemostasis, 10.1177/107602960100700111, 7:1, (53-57), Online publication date: 1-Jan-2001. Celis H, Thijs L, Staessen J, Birkenhäger W, Bulpitt C, de Leeuw P, Leonetti G, Nachev C, Tuomilehto J and Fagard R (2001) Interaction between nonsteroidal anti-inflammatory drug intake and calcium-channel blocker-based antihypertensive treatment in the Syst-Eur trial, Journal of Human Hypertension, 10.1038/sj.jhh.1001235, 15:9, (613-618), Online publication date: 1-Sep-2001. Calverley D (2001) Antiplatelet therapy in the elderly, Clinics in Geriatric Medicine, 10.1016/S0749-0690(05)70104-X, 17:1, (31-48), Online publication date: 1-Feb-2001. Straus W and Ofman J (2001) GASTROINTESTINAL TOXICITY ASSOCIATED WITH NONSTEROIDAL ANTI-INFLAMMATORY DRUGS, Gastroenterology Clinics of North America, 10.1016/S0889-8553(05)70219-3, 30:4, (895-920), Online publication date: 1-Dec-2001. Cairns J, Théroux P, Lewis H, Ezekowitz M and Meade T (2001) Antithrombotic Agents in Coronary Artery Disease, Chest, 10.1378/chest.119.1_suppl.228S, 119:1, (228S-252S), Online publication date: 1-Jan-2001. Sauaia A, Ralston D, Schluter W, Marciniak T, Havranek E and Dunn T (2016) Influencing Care in Acute Myocardial Infarction: A Randomized Trial Comparing 2 Types of Intervention, American Journal of Medical Quality, 10.1177/106286060001500503, 15:5, (197-206), Online publication date: 1-Sep-2000. Peterson J, Topol E, Sapp S, Young J, Lincoff A and Lauer M (2000) Evaluation of the effects of aspirin combined with angiotensin-converting enzyme inhibitors in patients with coronary artery disease, The American Journal of Medicine, 10.1016/S0002-9343(00)00492-7, 109:5, (371-377), Online publication date: 1-Oct-2000. Stemme V, Swedenborg J, Claesson H and Hansson G (2000) Expression of Cyclo-oxygenase-2 in Human Atherosclerotic Carotid Arteries, European Journal of Vascular and Endovascular Surgery, 10.1053/ejvs.2000.1145, 20:2, (146-152), Online publication date: 1-Aug-2000. Rubattu S, Giliberti R and Volpe M (2000) Etiology and pathophysiology of stroke as a complex trait, American Journal of Hypertension, 10.1016/S0895-7061(00)01249-8, 13:10, (1139-1148), Online publication date: 1-Oct-2000. Karila-Cohen D and Steg P (2000) Aspirine et prévention du risque cardiovasculaire, La Revue de Médecine Interne, 10.1016/S0248-8663(00)88723-8, 21, (S35-S40), Online publication date: 1-Mar-2000. Hersh E, Moore P and Ross G (2000) Over-the-counter analgesics and antipyretics: A critical assessment, Clinical Therapeutics, 10.1016/S0149-2918(00)80043-0, 22:5, (500-548), Online publication date: 1-May-2000. Tsang T, Barnes M, Gersh B and Hayes S (2000) Risks of Coronary Heart Disease in Women: Current Understanding and Evolving Concepts, Mayo Clinic Proceedings, 10.4065/75.12.1289, 75:12, (1289-1303), Online publication date: 1-Dec-2000. MacCallum P and Meade T (1999) Haemostatic function, arterial disease and the prevention of arterial thrombosis, Best Practice & Research Clinical Haematology, 10.1053/beha.1999.0041, 12:3, (577-599), Online publication date: 1-Sep-1999. Alexander R (1999) Treating hypertension: How low is optimal and does aspirin help?, Current Hypertension Reports, 10.1007/s11906-999-0074-x, 1:1, (59-61), Online publication date: 1-Jan-1999. Bernat A, Hoffmann P, Savi P, Lalé A and Herbert J (1999) Interspecies Comparison of the Antiplatelet, Antithrombotic, and Hemorrhagic Effects of SR 121566A, a Novel Nonpeptide GP IIb/IIIa Antagonist, Journal of Cardiovascular Pharmacology, 10.1097/00005344-199906000-00010, 33:6, (897-904), Online publication date: 1-Jun-1999. Modi N, Novotny W, Reimann J, Cannon C and Braunwauld E (2013) Pharmacokinetics and Pharmacodynamics of Sibrafiban, an Orally Administered IIb/IIIa Antagonist, in Patients with Acute Coronary Syndrome, The Journal of Clinical Pharmacology, 10.1177/00912709922008317, 39:7, (675-684), Online publication date: 1-Jul-1999. Meade T (1999) Risk of major gastrointestinal bleeding with aspirin, The Lancet, 10.1016/S0140-6736(05)76186-9, 353:9147, (149), Online publication date: 1-Jan-1999. Hennekens C (1999) Update on aspirin in the treatment and prevention of cardiovascular disease, American Heart Journal, 10.1016/S0002-8703(99)70391-1, 137:4, (S9-S13), Online publication date: 1-Apr-1999. Calverley D and Roth G (1999) Aspirin, Prostaglandins and Platelet Function: Pharmacology and Thrombosis Prevention Handbook of Platelet Physiology and Pharmacology, 10.1007/978-1-4615-5049-5_22, (478-494), . Al-Khadra A, Salem D, Rand W, Udelson J, Smith J and Konstam M (1998) Antiplatelet Agents and Survival: A Cohort Analysis From the Studies of Left Ventricular Dysfunction (SOLVD) Trial, Journal of the American College of Cardiology, 10.1016/S0735-1097(97)00502-0, 31:2, (419-425), Online publication date: 1-Feb-1998. Cairns J, Théroux P, Lewis H, Ezekowitz M, Meade T and Sutton G (1998) Antithrombotic Agents in Coronary Artery Disease, Chest, 10.1378/chest.114.5_Supplement.611S, 114:5, (611S-633S), Online publication date: 1-Nov-1998. Meade T and Brennan P (1998) Interpretation of Thrombosis Prevention Trial, The Lancet, 10.1016/S0140-6736(05)79156-X, 351:9110, (1206-1207), Online publication date: 1-Apr-1998. Friedman L, Furberg C and DeMets D (1998) Issues in Data Analysis Fundamentals of Clinical Trials, 10.1007/978-1-4757-2915-3_16, (284-322), . Fricchione G, Bilfinger T and Stefano G (1998) Aspirin inhibits granulocyte and monocyte adherence to saphenous vein endothelia in a process not mediated by nitric oxide, International Journal of Cardiology, 10.1016/S0167-5273(98)00033-3, 64, (S29-S33), Online publication date: 1-Apr-1998. (1998) Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease in men at increased risk, The Lancet, 10.1016/S0140-6736(97)11475-1, 351:9098, (233-241), Online publication date: 1-Jan-1998. Rebello S, Huang J, Shiu W, Saito K, Kaneko M, Saitoh Y and Lucchesi B (1998) Pharmacokinetics and Pharmacodynamics of SM-20302, a GPIIb/IIIa Receptor Antagonist, in Anesthetized Dogs, Journal of Cardiovascular Pharmacology, 10.1097/00005344-199809000-00021, 32:3, (485-494), Online publication date: 1-Sep-1998. Calverley D and Roth G (1998) ANTIPLATELET THERAPY, Hematology/Oncology Clinics of North America, 10.1016/S0889-8588(05)70051-4, 12:6, (1231-1249), Online publication date: 1-Dec-1998. Hennekens C (1998) RISK FACTORS FOR CORONARY HEART DISEASE IN WOMEN, Cardiology Clinics, 10.1016/S0733-8651(05)70378-7, 16:1, (1-8), Online publication date: 1-Feb-1998. Hansson L, Zanchetti A, Carruthers S, Dahlöf B, Elmfeldt D, Julius S, Ménard J, Rahn K, Wedel H and Westerling S (1998) Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial, The Lancet, 10.1016/S0140-6736(98)04311-6, 351:9118, (1755-1762), Online publication date: 1-Jun-1998. Hochman J, McCabe C, Stone P, Becker R, Cannon C, DeFeo-Fraulini T, Thompson B, Steingart R, Knatterud G and Braunwald E (1997) Outcome and Profile of Women and Men Presenting With Acute Coronary Syndromes: A Report From TIMI IIIB fn1fn1The TIMI IIIB Clinical Centers were supported by Grant R01-HL42311, the Central Units by Grant R01-HL42419 and the Data Coordinating Center by Grant R01-HL42428 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland., Journal of the American College of Cardiology, 10.1016/S0735-1097(97)00107-1, 30:1, (141-148), Online publication date: 1-Jul-1997. Dhein S, Gottwald M, Gottwald E, Hohlfeld T, Salameh A and Klaus W (1997) Acetylsalicylic acid enhances arrhythmogeneity in a model of local ischemia of isolated rabbit hearts, European Journal of Pharmacology, 10.1016/S0014-2999(97)01382-4, 339:2-3, (129-139), Online publication date: 1-Nov-1997. Mattsson C, Björkman J and Ulvinge J (1997) Melagatran, hirudin and heparin as adjuncts to tissue-type plasminogen activator in a canine model of coronary artery thrombolysis, Fibrinolysis and Proteolysis, 10.1016/S0268-9499(97)80056-2, 11:3, (121-128), Online publication date: 1-May-1997. Hoffmann P, Bernat A, Savi P and Herbert J (1997) Antiplatelet and Antithrombotic Efficacy of SR 121787, a Nonpeptide Orally Active GP IIb/IIIa Antagonist, in Rabbits: Comparison with Clopidogrel and Aspirin, Journal of Cardiovascular Pharmacology, 10.1097/00005344-199709000-00014, 30:3, (360-366), Online publication date: 1-Sep-1997. Smith W and DeWitt D (1997) Prostaglandin endoperoxide synthase isozymes , 10.1016/S1874-5245(97)80011-0, (227-260), . Higashiura K, Mathur R and Halushka P (1997) Gender-Related Differences in Androgen Regulation of Thromboxane A2 Receptors in Rat Aortic Smooth-Muscle Cells, Journal of Cardiovascular Pharmacology, 10.1097/00005344-199703000-00002, 29:3, (311-315), Online publication date: 1-Mar-1997. Hermida R, Fernández J, Ayala D, Mojón A and Iglesias M (2009) Influence of Aspirin Usage on Blood Pressure: Dose and Administration-Time Dependencies, Chronobiology International, 10.3109/07420529709001452, 14:6, (619-637), Online publication date: 1-Jan-1997. Hennekens C (1997) ASPIRIN IN THE TREATMENT AND PREVENTION OF CARDIOVASCULAR DISEASE, Annual Review of Public Health, 10.1146/annurev.publhealth.18.1.37, 18:1, (37-49), Online publication date: 1-May-1997. Kaplan S, Kaplan A, Marcoe K, Hammond W, Fisher L and Sauvage L (2016) Citric Acid Enhances the Antithrombotic Effect of Aspirin in Many Aspirin-Resistant Subjects, Clinical and Applied Thrombosis/Hemostasis, 10.1177/107602969700300108, 3:1, (54-57), Online publication date: 1-Jan-1997. Harpaz D, Benderly M, Goldbourt U, Kishon Y and Behar S (1996) Effect of aspirin on mortality in women with symptomatic or silent myocardial ischemia, The American Journal of Cardiology, 10.1016/S0002-9149(96)00598-X, 78:11, (1215-1219), Online publication date: 1-Dec-1996. Herholz H, Goff D, Ramsey D, Chan F, Ortiz C, Labarthe D and Nichaman M (1996) Women and mexican Americans receive fewer cardiovascular drugs following myocardial infarction than men and non-hispanic whites: The Corpus Christi Heart Project, 1988–1990, Journal of Clinical Epidemiology, 10.1016/0895-4356(95)00572-2, 49:3, (279-287), Online publication date: 1-Mar-1996. Venema D, Hollman P, Janssen K and Katan M (1996) Determination of Acetylsalicylic Acid and Salicylic Acid in Foods, Using HPLC with Fluorescence Detection, Journal of Agricultural and Food Chemistry, 10.1021/jf950458y, 44:7, (1762-1767), Online publication date: 1-Jan-1996. Wityak J and Sielecki T (2008) Section Review: Cardiovascular & Renal: Glycoprotein IIb/IIIa antagonists, Expert Opinion on Therapeutic Patents, 10.1517/13543776.6.11.1175, 6:11, (1175-1194), Online publication date: 1-Nov-1996. Nuovo J (1996) Ischemic Heart Disease Fundamentals of Family Medicine, 10.1007/978-1-4757-2535-3_12, (252-281), . Blockmans D, Deckmyn H and Vermylen J (1995) Platelet actuation, Blood Reviews, 10.1016/0268-960X(95)90020-9, 9:3, (143-156), Online publication date: 1-Sep-1995. Folts J (1995) Drugs for the prevention of coronary thrombosis: From an animal model to clinical trials, Cardiovascular Drugs and Therapy, 10.1007/BF00878571, 9:S1, (31-43), Online publication date: 1-Jan-1995. Fletcher A (2016) The Epidemiology of Cardiovascular Disease in Women, Vascular Medicine Review, 10.1177/1358863X9500600103, vmr-6:1, (17-31), Online publication date: 1-Feb-1995. Eisenberg P (1995) Novel antithrombotic strategies for the treatment of coronary artery thrombosis: A critical appraisal, Journal of Thrombosis and Thrombolysis, 10.1007/BF01060733, 1:3, (237-249), . van de Loo J and Stenzinger W (1995) Antithrombotic prophylaxis in arterial and venous vessel diseases, Fibrinolysis, 10.1016/S0268-9499(08)80013-6, 9, (58-65), Online publication date: 1-Apr-1995. Cairns J, Lewis H, Meade T, Sutton G and Théroux P (1995) Antithrombotic Agents in Coronary Artery Disease, Chest, 10.1378/chest.108.4_Supplement.380S, 108:4, (380S-400S), Online publication date: 1-Oct-1995. Benedek I, Joshi A, Pieniaszek H, King S and Kornhauser D (2013) Variability in the Pharmacokinetics and Pharmacodynamics of Low Dose Aspirin in Healthy Male Volunteers, The Journal of Clinical Pharmacology, 10.1002/j.1552-4604.1995.tb04044.x, 35:12, (1181-1186), Online publication date: 1-Dec-1995. Eisenberg P (1994) Thrombosis and Fibrinolysis in Acute M

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