A simple and reliable method of chromosome banding for prenatal cytogenetics using a bromodeoxyuridine pulse
1983; Wiley; Volume: 3; Issue: 4 Linguagem: Inglês
10.1002/pd.1970030405
ISSN1097-0223
AutoresSam Z. Eichenbaum, E.J. Krumins,
Tópico(s)Metabolism and Genetic Disorders
ResumoAn extremely simple, fully defined and reliable technique for banding chromosomes in situ is described. The method uses a pulse of bromodeoxyuridine to produce replication pattern banding complete with G- and C-type banding in the same karyotype. This enables immediate resolution of problems otherwise requiring extra subculturing and the application of conventional banding techniques. The value of routine chromosome banding in prenatal cytogenetics using such an economical technique is discussed.
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